Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Progress in Charge Transfer in 2D Metal Halide Perovskite Heterojunctions: A Review. [PDF]
Quan C +5 more
europepmc +1 more source
Active site labeling of fatty acid and polyketide acyl-carrier protein transacylases
Tony D. Davis +2 more
openalex +2 more sources
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
A New Method for Screening Thalassemia Patients Using Mid-Infrared Spectroscopy. [PDF]
Thumanu K +12 more
europepmc +1 more source
Characteristics of Corn Cobs Waste Activated Carbon for Slow Release Micro Fertilizer Carrier
Priyadi Priyadi, Windu Mangiring
openalex +2 more sources
801 DIAGNOSIS AND CARRIER DETECTION OF TAY-SACHS DISEASE USING SULFATED FLUOROGENIC SUBSTRATES: DIRECT DETERMINATION OF HEXOSAMINIDASE A IN SERUM DURING PREGNANCY AND IN THE PRESENCE OF HEREDITARY HEATLABILE HEXOSAMINIDASE B [PDF]
Yoav Ben‐Yoseph +2 more
openalex +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Every Picture Tells a Story: Visual Alternatives to Oral Tradition in Ponam Society [PDF]
James Carrier, Achsah Carrier
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