Results 201 to 210 of about 3,333,286 (392)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Carrier screening for multiple complex monogenic diseases using long-read sequencing: a population-based study of premarital couples in Shanghai. [PDF]

Hum Genomics
Hua R, Li S, Cui D, Lu Y, Li Y, Lin Y, Gao L, Lv S, Ma R, Mao A, Han X, Wang J, Wang Y.   +12 more
europepmc   +1 more source

Formic Acid as a Hydrogen Energy Carrier

, 2017
J. Eppinger, Kuo‐Wei Huang
semanticscholar   +1 more source

Semiconducting Group 15 Monolayers: A Broad Range of Band Gaps and High Carrier Mobilities.

Angewandte Chemie, 2016
S. Zhang, Meiqiu Xie, Fengyu Li, Zhong Yan, Yafei Li, E. Kan, Wei Liu, Zhongfang Chen, H. Zeng   +8 more
semanticscholar   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

A nanolaser with extreme dielectric confinement. [PDF]

Sci Adv
Xiong M, Yu Y, Berdnikov Y, Borregaard SK, Dubré AH, Semenova E, Yvind K, Mørk J.   +7 more
europepmc   +1 more source

Investigation into the Exciton Binding Energy of Carbon Nitrides on Band Structure and Carrier Concentration through the Photoluminescence Effect [PDF]

Zhiyou Lin, Xu Cai, Wei Lin
openalex   +1 more source

Harnessing albumin as a carrier for cancer therapies

Advanced Drug Delivery Reviews, 2018
Ella N. Hoogenboezem, C. Duvall
semanticscholar   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Reproductive carrier screening for genetic disorders: position statement of the Canadian College of Medical Geneticists. [PDF]

J Med Genet
Aul RB, Canales KE, De Bie I, Laberge AM, Langlois S, Nelson TN, Walji S, Yu AC, Lazier J, Canadian College of Medical Geneticists, Canadian College of Medical Geneticists .   +10 more
europepmc   +1 more source