Results 81 to 90 of about 5,925,887 (294)

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Practical issues and some lessons learned from realization of phase sensitive parametric regenerators

Practical issues in pump phase synchronization necessary for coherent all-optical processing are discussed, including feed-forward carrier recovery of phase encoded ...
Slavík, Radan, Richardson, David J., Kakande, Joseph   +2 more
core   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Modified Decision Feedback Equalizers for Nonlinearity Compensation in Coherent PAM4 Transmission System

Photonics
To address chromatic dispersion (CD) and nonlinear impairments in coherent optical four-level pulse amplitude modulation (PAM4) systems, we propose a magnitude-assisted decision feedback equalizer (MA-DFE).
Zhengxuan Li, Zheng Xin, Siyu Luo, Acai Tan, Bingyao Cao   +4 more
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Phase-level synchronization for physical-layer network coding [PDF]

, 2012
Physical-layer network coding (PNC) brings throughput improvement for wireless networks. However, its synchronization requirement is widely recognized as an obstacle to its implementation.
Song, Q, Abbas Jamalipour, Huang, Y, Qingyang Song, Shiqiang Wang, Wang, S, Jamalipour, A, Yang Huang   +7 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Close-form expression of one-tap normalized LMS carrier phase recovery in optical communication systems [PDF]

, 2016
The performance of long-haul high speed coherent optical fiber communication systems is significantly degraded by the laser phase noise and the equalization enhanced phase noise (EEPN).
Zhang, Yimo, Tiegen Liu, Popov, S, Liu, T, Li, J, Sergei Popov, Jie Li, Zhang, Y, Popov, Sergei,, Zhang, Yimo,, Xu, T, Gunnar Jacobsen, Xu, Tianhua,, Jacobsen, Gunnar,, Yimo Zhang, Tianhua Xu, Li, Jie,, Li, Jie, Xu, Tianhua, Jacobsen, Gunnar, Liu, Tiegen, Popov, Sergei, Liu, Tiegen,, Jacobsen, G   +23 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source