Results 91 to 100 of about 6,669,484 (371)
The iron-sulfur cluster assembly machineries in plants: current knowledge and open questions
Many metabolic pathways and cellular processes occurring in most sub-cellular compartments depend on the functioning of iron-sulfur (Fe-S) proteins, whose cofactors are assembled through dedicated protein machineries.
Jérémy eCouturier+4 more
doaj +1 more source
Abstract A number of analogues of Escherichia coli apo-acyl carrier protein (apo-ACP) have been synthesized by the solid phase method. A standard isolation procedure was used for all analogues. This involved cleavage from the solid support and deprotection by treatment of the peptide-resin with hydrogen bromide and trifluoroacetic acid. The product was
Garland R. Marshall+2 more
openaire +3 more sources
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
The transport of HDL cholesteryl esters (CE) from plasma to the liver involves a direct uptake pathway, mediated by hepatic scavenger receptor B-I (SR-BI), and an indirect pathway, involving the exchange of HDL CE for triglycerides (TG) of TG-rich ...
Xavier Collet+8 more
doaj
Membrane‐Based Olefin/Paraffin Separations
Efficient olefin/paraffin separation is a grand challenge because of their similar molecular sizes and physical properties, and is also a priority in the modern chemical industry.
Yanxiong Ren+9 more
doaj +1 more source
Diseases Caused by Mutations in Mitochondrial Carrier Genes SLC25: A Review
In the 1980s, after the mitochondrial DNA (mtDNA) had been sequenced, several diseases resulting from mtDNA mutations emerged. Later, numerous disorders caused by mutations in the nuclear genes encoding mitochondrial proteins were found. A group of these
Ferdinando Palmieri+2 more
doaj +1 more source
Beta Thalassemia Carriers detection empowered federated Learning [PDF]
Thalassemia is a group of inherited blood disorders that happen when hemoglobin, the protein in red blood cells that carries oxygen, is not made enough. It is found all over the body and is needed for survival. If both parents have thalassemia, a child's chance of getting it increases.
arxiv
Archaeal ApbC/Nbp35 Homologs Function as Iron-Sulfur Cluster Carrier Proteins
Iron-sulfur clusters may have been the earliest catalytic cofactors on earth, and most modern organisms use them extensively. Although members of the Archaea produce numerous iron-sulfur proteins, the major cluster assembly proteins found in the Bacteria
J. Boyd+3 more
semanticscholar +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source