Results 81 to 90 of about 8,126,655 (341)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

The Suppressor of AAC2 Lethality SAL1 Modulates Sensitivity of Heterologously Expressed Artemia ADP/ATP Carrier to Bongkrekate in Yeast [PDF]

, 2013
The ADP/ATP carrier protein (AAC) expressed in Artemia franciscana is refractory to bongkrekate. We generated two strains of Saccharomyces cerevisiae where AAC1 and AAC3 were inactivated and the AAC2 isoform was replaced with Artemia AAC containing a ...
A Keller, A Kemp Jr, A Shevchenko, AA Starkov, AL Goldstein, Andrea M. Hunt, B Cooper, B Guerin, B Hoffmann, B Kucejova, Beata Torocsik, C Chinopoulos, C Chinopoulos, C Janke, C Konrad, C Konrad, Christos Chinopoulos, CP Smith, Cynthia L. David, D De Stefani, DJ Pagliarini, F Jiang, G Arselin, G Brandolin, G Szabadkai, G Woldegiorgis, George Tsaprailis, GJ Lauquin, H Aquila, I Amigo, J Clegg, J Laco, J Traba, J Traba, JA Reynolds, JE Kokoszka, Jeffrey L. Brodsky, JJ Lemasters, JK Eng, JM Baughman, K Beyer, Karoly Vekey, KE Kwast, Lilla Turiak, M Bonora, M Klingenberg, M Rak, M Rey, MA Menze, Monika Wysocka-Kapcinska, NL Andon, NN Zheleznova, O Ozohanics, PJ Henderson, R Craig, R Kramer, R Parvin, RA Haworth, RD Gietz, RK Emaus, Roza Kucharczyk, S Cavero, S Manon, S Uribe, SC Hand, T Hamazaki, TM Rickey, UK Laemmli, V Giorgio, Vera Adam-Vizi, WJ Qian, XJ Chen   +71 more
core   +4 more sources

Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier.

Polymers, 2011
In past two decades poly lactic-co-glycolic acid (PLGA) has been among the most attractive polymeric candidates used to fabricate devices for drug delivery and tissue engineering applications.
Hirenkumar K. Makadia, S. Siegel
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Membrane‐Based Olefin/Paraffin Separations

Advanced Science, 2020
Efficient olefin/paraffin separation is a grand challenge because of their similar molecular sizes and physical properties, and is also a priority in the modern chemical industry.
Yanxiong Ren, Xu Liang, Haozhen Dou, Chumei Ye, Zheyuan Guo, Jianyu Wang, Yichang Pan, Hong Wu, Michael D. Guiver, Zhongyi Jiang   +9 more
doaj   +1 more source

Diseases Caused by Mutations in Mitochondrial Carrier Genes SLC25: A Review

Biomolecules, 2020
In the 1980s, after the mitochondrial DNA (mtDNA) had been sequenced, several diseases resulting from mtDNA mutations emerged. Later, numerous disorders caused by mutations in the nuclear genes encoding mitochondrial proteins were found. A group of these
Ferdinando Palmieri, Pasquale Scarcia, Magnus Monné   +2 more
doaj   +1 more source

Distinct steps in the import of ADP/ATP carrier into mitochondria [PDF]

, 1987
Transport of the precursor to the ADP/ATP carrier from the cytosol into the mitochondrial inner membrane was resolved into several consecutive steps. The precursor protein was trapped at distinct stages of the import pathway and subsequently chased to ...
Neupert, Walter, Pfanner, Nikolaus
core  

Preclinical studies on new proteins as carrier for glycoconjugate vaccines.

Vaccine, 2016
Glycoconjugate vaccines are made of carbohydrate antigens covalently bound to a carrier protein to enhance their immunogenicity. Among the different carrier proteins tested in preclinical and clinical studies, five have been used so far for licensed ...
M. Tontini, M. R. Romano, D. Proietti, E. Balducci, F. Micoli, C. Balocchi, L. Santini, V. Masignani, F. Berti, Paolo Costantino   +9 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source