Exploring the compatibility of phosphopantetheinyl transferases with acyl carrier proteins spanning type II polyketide synthase sequence space. [PDF]
Bifendeh ALN +52 more
europepmc +1 more source
Chemosensory proteins as putative semiochemical carriers in the desert isopod Hemilepistus reaumurii
Alessio Iannucci +7 more
openalex +2 more sources
Cellular uptake of steroid carrier proteins—Mechanisms and implications
T. Willnow, A. Nykjaer
semanticscholar +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Mutagenesis Supports AlphaFold Prediction of How Modular Polyketide Synthase Acyl Carrier Proteins Dock With Downstream Ketosynthases. [PDF]
Hirsch M +3 more
europepmc +1 more source
Archaeal ApbC/Nbp35 Homologs Function as Iron-Sulfur Cluster Carrier Proteins
J. Boyd +3 more
semanticscholar +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Multimeric, multivalent fusion carrier proteins for site-selective glycoconjugate vaccines simultaneously targeting <i>Staphylococcus aureus</i> and <i>Pseudomonas aeruginosa</i>. [PDF]
Sorieul C +11 more
europepmc +1 more source

