Results 231 to 240 of about 8,126,655 (341)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Multimeric, multivalent fusion carrier proteins for site-selective glycoconjugate vaccines simultaneously targeting <i>Staphylococcus aureus</i> and <i>Pseudomonas aeruginosa</i>. [PDF]

Chem Sci
Sorieul C, Mikladal B, Wu DY, Brogioni B, Giovani C, Adamo G, Romagnoli G, Margarit Y Ros I, Codée J, Romano MR, Carboni F, Adamo R.   +11 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Effects of long-term dehydration and quick rehydration on the camel kidney: pathological changes and modulation of the expression of solute carrier proteins and aquaporins. [PDF]

BMC Vet Res
Damir HA, Ali MA, Adem MA, Amir N, Ali OM, Tariq S, Adeghate E, Greenwood MP, Lin P, Alvira-Iraizoz F, Gillard B, Murphy D, Adem A.   +12 more
europepmc   +1 more source

Direct acylation of carrier proteins with functionalized beta-lactones.

Organic Letters, 2010
J. Amoroso, Lawrence S. Borketey, Gitanjeli Prasad, N. A. Schnarr   +3 more
semanticscholar   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Important Features for Protein Foldings in Two Acyl Carrier Proteins from Enterococcus faecalis. [PDF]

J Microbiol Biotechnol
Yoo S, Yeon J, Kim E, Kim Y.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Distal peptide elongation by a protease-like ligase and two distinct carrier proteins.

Chem
Gude F, Bohne A, Dell M, Franke J, Dunbar KL, Groll M, Hertweck C.   +6 more
europepmc   +1 more source

Functional redundancy of ubiquitin-like sulfur-carrier proteins facilitates flexible, efficient sulfur utilization in the primordial archaeon <i>Thermococcus kodakarensis</i>. [PDF]

mBio
Hidese R, Ohira T, Sakakibara S, Suzuki T, Shigi N, Fujiwara S.   +5 more
europepmc   +1 more source