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The structural role of the carrier protein – active controller or passive carrier

Natural Product Reports, 2012
Common to all FASs, PKSs and NRPSs is a remarkable component, the acyl or peptidyl carrier protein (A/PCP). These take the form of small individual proteins in type II systems or discrete folded domains in the multi-domain type I systems and are characterized by a fold consisting of three major α-helices and between 60-100 amino acids.
Crosby, John, Crump, Matthew P.
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Sterol carrier and lipid transfer proteins

Chemistry and Physics of Lipids, 1985
The discovery of the sterol carrier and lipid transfer proteins was largely a result of the findings that cells contained cytosolic factors which were required either for the microsomal synthesis of cholesterol or which could accelerate the transfer or exchange of phospholipids between membrane preparations.
George V. Vahouny   +5 more
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Liposomes as Protein Carriers in Immunology

Journal of Liposome Research, 2004
Liposomes are excellent carriers for protein antigens since they can contain large amounts of antigen, potentially in association with adjuvants. Liposomes may be made to mimic the pathogens that stimulated the evolution of the immune system. As such, numerous mechanisms exist to promote their uptake by antigen presenting cells and exposure of ...
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Chitosan-Alginate Microparticles as a Protein Carrier

Drug Development and Industrial Pharmacy, 2001
The oral administration of peptidic drugs requires their protection from degradation in the gastric environment and the improvement of their absorption in the intestinal tract. For these requirements, a microsystem based on cross-linked alginate as the carrier of bovine serum albumin (BSA), used as a model protein, was proposed.
COPPI, Gilberto   +4 more
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Oxygen carrier proteins

1985
The authors wish to dedicate this article to the memory of Professor Eraldo Antonini, who died of an incurable illness on 19 March 1983. It was Professor Antonini who introduced the authors to the study of oxygen-carrying proteins and inspired their scientific activity.
Maurizio Brunori   +2 more
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Acyl carrier protein interacts with melittin

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1990
Acyl carrier protein (ACP) from Escherichia coli has been shown to form complexes with melittin, a cationic peptide from bee venom. ACP is a small (Mr 8847), acidic, Ca2(+)-binding protein, which possesses some characteristics resembling those of regulatory Ca2(+)-binding proteins including interaction with melittin. Complexing between melittin and ACP
Ernst-Fonberg, Mary L.   +2 more
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Efficacy of Food Proteins as Carriers for Flavonoids

Journal of Agricultural and Food Chemistry, 2012
Enrichment of flavonoids in food is often limited by their off-tastes, which might be counteracted by the use of food proteins as carriers of flavonoids. Various milk proteins, egg proteins, and gelatin hydrolysates were compared for their binding characteristics to two flavan-3-ols.
Bohin, M.C.   +3 more
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Dialectics in carrier research: The ADP/ATP carrier and the uncoupling protein

Journal of Bioenergetics and Biomembranes, 1993
A concise review is given of the research in our laboratory on the ADP/ATP carrier (AAC) and the uncoupling protein (UCP). Although homologous proteins, their widely different functions and contrasts are stressed. The pioneer role of research on the AAC, not only for the mitochondrial but also for other carriers, and the present state of their ...
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Trace elements and carrier proteins in the aged

Archives of Gerontology and Geriatrics, 1994
Serum level of trace elements can be used as a marker for diagnosis and management of diseases. We evaluated the effects of age, sex and diurnal rhythm on serum concentration of Cu, Fe, Zn and their carrier proteins. The subjects (N=336) were participants of the randomized multidisciplinary Berlin Aging Study (BASE), stratified for age (70-103 yrs) and
Sabine Fimmel   +3 more
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Macromolecular complexes of amino acid:[carrier protein] ligases and carrier proteins

2012
Aminoacyl-tRNA synthetases have well established and fundamental role in protein biosynthesis. They catalyze attachment of amino acids to cognate tRNAs, which are subsequently used as substrates for the ribosomal translation of mRNA. We have recently discovered and characterized bacterial homologs of atypical archaeal seryl-tRNA synthetases (aSerRS ...
Ivić, Nives   +3 more
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