Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Thermoresponsive Solid Dispersion to Enhance Dissolution Profile of Atorvastatin Calcium: An Industrially Sustainable Alternative to Conventional Approaches. [PDF]
Sherif AY, Ibrahim MA.
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Spin-State Control of CO<sub>2</sub> Photoreduction on Defective TiO<sub>2</sub>: Decoupling Hydrogenation Selectivity and Charge Recombination. [PDF]
Yan X, Zhang L, He J, Long R.
europepmc +1 more source
Interfacial Electronic Interactions in Graphene Quantum Dot/MXene Systems and Their Consequences for Optical Response. [PDF]
Kumar A +7 more
europepmc +1 more source
Ta-induced electronic reconstruction in CaSiO<sub>3</sub>: wide-band-gap modulation, emergent metallic behavior, and multifunctional response from first-principles. [PDF]
Rafiq Q +5 more
europepmc +1 more source
Progress on Synergistic Enhancement of Perovskite Solar Cell Efficiency and Stability via Defect Engineering and Carrier Dynamics Optimization. [PDF]
Wang D, Gu W, Li Q, Du B, Wang L.
europepmc +1 more source
Random-Forest-Based Smartphone GNSS Position Correction Using Satellite-Wise LOS Projection Error Estimation and Exponential Temporal WLS. [PDF]
Jang K, Seo K.
europepmc +1 more source

