Results 61 to 70 of about 441,417 (303)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Hepatitis B Virus: Inactive carriers

open access: yesVirology Journal, 2005
Inactive carriers forms the largest group in chronic HBV infected patients. Around 300 million people are inactive carriers The inactive HBsAg carrier state is diagnosed by absence of HBeAg and presence of anti-HBe, undetectable or low levels of HBV DNA ...
Saini Nitin   +2 more
doaj   +1 more source

Structure, substrate binding, and symmetry of the mitochondrial ADP/ATP carrier in its matrix-open state [PDF]

open access: bronze, 2021
Joel José Montalvo‐Acosta   +4 more
openalex   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Motor carrier news

open access: yes, 1996
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.May 1996-Title from captionMode of access: Internet from the

core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The Mute Zone of the Social Representations about the Person with HIV/AIDS: Normative and Counternormative Elements of the Social Thinking

open access: yesPsicologia, 2007
This is a quali-quantitative and descriptive study. Its objective is analyze the content and the structure of the social representations of nurses about the person with HIV/AIDS, considering the explicit and masked elements (mute zone). The subjects were
Denize Cristina de Oliveira   +1 more
doaj  

Truck drivers guide book

open access: yes, 2005
Title from p. [1] of PDF document (viewed May 12, 2006).; "10-0446-00 OHP1210 02/05"--P. 4.; Harvested from the web on 5/12/06The Office of Licensing and Commercial Standards of the Ohio State Highway Patrol has prepared this Truck drivers guide book as ...
Ohio State Highway Patrol. Motor Carrier Enforcement Unit.
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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