Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
In the Brazilian Chamber of Deputies, an absolute majority may bring any bill out of committee and to the floor for consideration without the committee’s report by approving an urgency petition.
Acir Almeida, Fabiano Santos
doaj
Challenges in Combating Cartels, 14 Years After the Enactment of Indonesian Competition Law [PDF]
Fourteen years after the enactment of Indonesian Competition Law, the public has had the chance to witness the enforcement practice of the Commission for the Supervision of Business Activities (the Kppu), the competition supervisory authority of ...
Sih Yuliana Wahyuningtyas
doaj
Company Tax Reform in Europe and its Effect on Collusive Behavior [PDF]
We study how harmonization of corporate tax systems affects the stability of international cartels. We show that tax base harmonization reinforces collusive agreements, while harmonization of corporate tax rates may destabilize or stabilize cartels.
Dirk Schindler, Guttorm Schjelderup
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Analyzing the number of articles with network meta-analyses using chord diagrams and temporal heatmaps over the past 10 years: Bibliometric analysis. [PDF]
Liang YE, Ho SY, Chien TW, Chou W.
europepmc +1 more source
STATISTICS ON MODERN PRIVATE INTERNATIONAL CARTELS, 1990-2005 [PDF]
This report explains the principal economic and legal features of a unique set of data on 283 modern private international cartels discovered anywhere in the world from January 1990 to the end of 2005.
C. Gustav Helmers, John Connor
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Using Rasch KIDMAP to identify whether China dominates the research area of computer science (CS) based on the specialization index of article citations: Bibliometric analysis. [PDF]
Yen PT, Chien TW, Chou W, Kan WC.
europepmc +1 more source
EXPORT CARTELS : A Developing Country Perspective [PDF]
Export cartels are exempted from the competition laws of most countries. While some scholars and several WTO members have recently condemned such cartels, others have argued that they allow efficiency gains that actually promote competition and trade ...
Aditya Bhattacharjea
core

