Results 121 to 130 of about 10,114 (290)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
THE PENALTIES FOR MONOPOLY BEHAVIOR – CARTELS
Acta Economica, 2010 Determining penalties for cartels and cartel behaviour is one of thr most important things that antitrust authorites has been engaged in world wide. Just a number of executed processing and fines in the last few years is growing, which clearly confirms ...
Младен Ребић, Мр
doaj
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
LENIENCY AND COOPERATION PROGRAMS IN BRAZIL: AN EMPIRICAL ANALYSIS FROM 1994 TO 2014
Revista de Economia ContemporâneaLeniency and cooperation programs are considered important instruments to assist in the effectiveness of the antitrust policy and they are designed to attend the following purposes: in the short run to facilitate detection of cartels and in the long run ...
Fernanda Mariana da Silva Lima +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Mexican drug cartels and international theory: history with solutions
, 2013 The struggle between the Mexican government and Mexican drug cartels has\ud reached a critical point with the death toll in several areas reaching levels comparable to\ud the failed-state of Afghanistan and war-torn Iraq.
Page, James
core
Using Rasch KIDMAP to identify whether China dominates the research area of computer science (CS) based on the specialization index of article citations: Bibliometric analysis. [PDF]
Medicine (Baltimore), 2023 Yen PT, Chien TW, Chou W, Kan WC.
europepmc +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Company Tax Reform in Europe and its Effect on Collusive Behavior [PDF]
We study how harmonization of corporate tax systems affects the stability of international cartels. We show that tax base harmonization reinforces collusive agreements, while harmonization of corporate tax rates may destabilize or stabilize cartels.
Guttorm Schjelderup, Dirk Schindler
core