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Lubrication of Articular Cartilage

Annual Review of Biomedical Engineering, 2016
The major synovial joints such as hips and knees are uniquely efficient tribological systems, able to articulate over a wide range of shear rates with a friction coefficient between the sliding cartilage surfaces as low as 0.001 up to pressures of more than 100 atm. No human-made material can match this. The means by which such surfaces maintain their
Sabrina, Jahn   +2 more
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CALCIFICATION IN ARTICULAR CARTILAGE

The Journal of Bone and Joint Surgery. British volume, 1960
A case of calcification of articular cartilage in association with a parathyroid tumour is described. Previously reported cases of articular calcification are briefly discussed, and it is recommended that patients with articular calcification of undetermined cause should be investigated for hyperparathyroidism.
G E, HOSKING, G, CLENNAR
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Regeneration of Articular Cartilage

2005
Loss of articular cartilage from the ends of bones forming diarthrodial joints can be the source of profound pain and disability, and eventually lead to complete degeneration of the joint, necessitating total joint replacement. Until a few years ago, there seemed little hope of treating such defects.
B, Kinner, R M, Capito, M, Spector
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Integrins in Articular Cartilage

2008
In the following sections, we primarily review our own work on the expression, tissue distribution and function of integrins in selected in vitro models of articular chondrocytes and limb bud mesenchymal cells. The expression pattern of α1-, α3-, αv- and α5β1-integrins and their specific ligand binding were investigated in monolayer cultures of ...
Shakibaei, M, Csaki, C, Mobasheri, A
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Fatigue of Articular Cartilage

Nature, 1973
IT has been suggested1 that fibrillation, the earliest change in osteoarthritic cartilage visible to the naked eye, may be the result of fatigue failure. Abnormally high stresses in the superficial layer of cartilage could be produced by unusually high applied loads, incongruity of the joint surface, or softening of the cartilage by mucopolysaccharide ...
B O, Weightman   +2 more
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Ultrastructure of articular cartilage

Zeitschrift f�r Zellforschung und Mikroskopische Anatomie, 1959
The present paper describes an electron microscopical investigation into the ultrastructure of patellary and femorocondylar articular cartilage from adult guinea pigs, mice and young rats. The following observations were made: 1. The intercellular matrix contains two varieties of collagen fibrils, one being 85 A in diameter and not striated, the ...
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Articular Cartilage Biology

Journal of the American Academy of Orthopaedic Surgeons, 2003
Articular cartilage is a complex tissue maintained by chondrocytes, which undergo metabolic changes as a result of aging, disease, and injury. These changes may hinder tissue maintenance and repair, resulting in accelerated loss of articular surface and leading to end-stage arthritis.
Michael, Ulrich-Vinther   +4 more
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Microfracture of Articular Cartilage

JBJS Reviews, 2016
➢ Microfracture is a treatment option for symptomatic, full-thickness cartilage defects.➢ Microfracture is most likely to be successful when performed in nonobese patients under the age of thirty years for small (<2 to 4-cm2) femoral condylar defects that have been symptomatic for a short time (less than twelve to twenty ...
Mark F, Sommerfeldt   +4 more
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Restoration of Articular Cartilage

Journal of Bone and Joint Surgery, 2014
➤ Novel (i.e., quantitative and semiquantitative) cartilage imaging techniques can evaluate cartilage composition to augment information obtained from traditional magnetic resonance imaging sequences that detail morphology.➤ A well-defined role for drugs leading to chondroprotection has not yet been determined.➤ Shortcomings of bone marrow stimulation ...
Cathal J, Moran   +6 more
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Articular Cartilage Repair

The American Journal of Sports Medicine, 1998
Articular cartilage can tolerate a tremendous amount of intensive and repetitive physical stress. However, it manifests a striking inability to heal even the most minor injury. Both the remarkable functional characteristics and the healing limitations reflect the intricacies of its structure and biology.
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