Results 81 to 90 of about 293,742 (284)

Designing Tissue Function Through Embedded Bioprinting Architectures

Advanced Science, EarlyView.
Embedded bioprinting enables soft, cell‐dense constructs to be fabricated within supporting bath environments. This review introduces a function‐guided framework linking target tissue functions to architectural requirements, supporting bath selection, bioink design, printing dynamics, and validation assays.
Qi Li, Yifei Cao, Jiaxin Lin, Huayong Yang, Hongzhao Zhou   +4 more
wiley   +1 more source

THE THERAPEUTIC TACTICS OF INTRA-ARTICULAR FRACTURES OF THE ANKLE (LITERATURE REVIEW)

Acta Biomedica Scientifica, 2013
As a result of the analysis of literature it was revealed that in case of pronation-abduction ankle injury takes place injury of the articular surfaces. The hyaline cartilage significantly suffers.
I. V. Zedgenidze, N. V. Tishkov
doaj  

Recent advances in MRI of the articular cartilage of the knee [PDF]

Zagazig University Medical Journal
Articular cartilage is a vital component of the joint, as it is frequently exposed to trauma and is affected by a number of conditions and diseases such as osteoarthritis and hemophilic arthropathy.
Doaa Abdelhakim, Gehan Lotfy, Mohammed Amin, Ahmed Issa   +3 more
doaj   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

Advanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie, Jie Huang, Chunhao Cao, Zhenchao Tang, Xingchen Li, Jianmin Guo, Xinxin Chen, Fang Wang, Dongyi He, Jie Li, Yu Du, Bing He, Jianhua Yao, Aiping Lu, Chao Liang   +14 more
wiley   +1 more source

Assessment of morphology, radiopacity gradient and mechanical properties of articular cartilage with contrast-enhanced high-resolution peripheral quantitative computed tomography

Frontiers in Bioengineering and Biotechnology
IntroductionDegenerative alterations in proteoglycans content and collagen structure compromise the mechanical integrity of articular cartilage and, therefore, its viscoelastic properties. Early detection of these subtle alterations is a prerequisite for
Simone Fantoni, Matteo Berni, Roberta Fognani, Giulia Fraterrigo, Paolo Cardarelli, Fabio Baruffaldi, Massimiliano Baleani   +6 more
doaj   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source

Hydrogel-Based 3D Bioprinting Technology for Articular Cartilage Regenerative Engineering

Gels
Articular cartilage is an avascular tissue with very limited capacity of self-regeneration. Trauma or injury-related defects, inflammation, or aging in articular cartilage can induce progressive degenerative joint diseases such as osteoarthritis.
Hongji Zhang, Zheyuan Zhou, Fengjie Zhang, Chao Wan   +3 more
doaj   +1 more source

Severe Phenotype in an Indian Family With Progressive Pseudorheumatoid Arthropathy of Childhood

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive pseudorheumatoid arthropathy of childhood (PPAC) is a rare autosomal recessive progressive condition that affects the cartilage of joints and bones. The symptoms of PPAC include stiffness of the joints, bony swelling of the toes and fingers, short stature, kyphosis, and muscle weakness.
Narinder Singh, Arpita Neogi, Liliane H. Gibbs, Jagdish Soni, Elizabeth Chao, Virginia Kimonis   +5 more
wiley   +1 more source

Postnatal development of depth-dependent collagen density in ovine articular cartilage [PDF]

, 2010
Articular cartilage (AC) is the layer of tissue that covers the articulating ends of the bones in diarthrodial joints. Adult AC is characterised by a depth-dependent composition and structure of the extracellular matrix that results in depth-dependent ...
Kranenbarg, S., Leeuwen, J.L., van, Barend van Lagen, Turnhout, van, M.C.; id_orcid, Han Zuilhof, van Leeuwen, J.L., Turnhout, van, M.C., Turnhout, M.C., van, van Lagen, B., Henk Schipper, van Turnhout, M.C., Schipper, H., Leeuwen, van, J.L., Turnhout, MC Mark van, Lagen, van, B., Schipper, H, Leeuwen, JL Johan van, Lagen, B., van, Zuilhof, Han, Zuilhof, H., Mark C van Turnhout, Sander Kranenbarg, Lagen, B van, Kranenbarg, S, Johan L van Leeuwen   +24 more
core   +2 more sources

Musculoskeletal Phenotypes of 19 Patients With X‐Linked HNRNPH2‐Related Neurodevelopmental Disorder: A Prospective Case Series

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Detailed clinical phenotypes have been previously reported for 33 individuals with X‐linked HNRNPH2‐related neurodevelopmental disorder. Of these, 75% self‐reported a musculoskeletal abnormality, including hip dysplasia, scoliosis, kyphosis, lordosis, pes planus, arthritis, and missing spinous processes.
Ambar Garcia, Rachel Salazar, Nicole Holuba, Franklin E. Paulino, Michael G. Vitale, Jennifer M. Bain, Joshua Hyman   +6 more
wiley   +1 more source