Results 121 to 130 of about 502,749 (311)
Advanced Materials Technologies, EarlyView.Electrospinning enables the hierarchical assembly of nanofiber‐based scaffolds for tissue engineering. However, encapsulated proteins often undergo structural changes. This study used mesoporous silica nanoparticles (MSNs) as protective carriers, mitigating protein denaturation and supporting controlled release.
Vera Citro +5 more
wiley +1 more source
Arthritis Research & TherapyBackground Previously, fragments from Sirtuin 1 (SIRT1) were identified in preclinical and clinical samples to display an increase in serum levels for N-terminal (NT) SIRT1 vs. C-terminal (CT) SIRT1, indicative of early signs of OA.
Miya Marco +6 more
doaj +1 more source
T1rho Fractional-order Relaxation of Human Articular Cartilage [PDF]
arXiv, 2019 T1rho imaging is a promising non-invasive diagnostic tool for early detection of articular cartilage degeneration. A mono-exponential model is normally used to describe the T1rho relaxation process. However, mono-exponentials may not adequately to describe NMR relaxation in complex, heterogeneous, and anisotropic materials, such as articular cartilage.
arxiv
Mechanochemistry: Fundamental Principles and Applications
Advanced Science, EarlyView.In this review, the physicochemical principles of mechanochemistry are first clarified. Based on this foundation, the research basis and cutting‐edge scientific achievements in four areas are introduced: solid‐state organic chemistry, polymers, interface science, and biomechanochemistry.
Liang Dong +4 more
wiley +1 more source
Accelerated Bone Healing via Electrical Stimulation
Advanced Science, EarlyView.Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun +4 more
wiley +1 more source
AIMS Medical Science, 2017 Objectives: The aim of this narrative review of the literature was to synthesize and comment the mechanisms of action of avocado/soybean unsaponifiable mixture (ASU-E, Piascledine®300) on articular tissues involved in the OA pathogenesis.
Yves Edgard Henrotin
doaj +1 more source
Knee Cartilage Segmentation Using Diffusion-Weighted MRI [PDF]
arXiv, 2019 The integrity of articular cartilage is a crucial aspect in the early diagnosis of osteoarthritis (OA). Many novel MRI techniques have the potential to assess compositional changes of the cartilage extracellular matrix. Among these techniques, diffusion tensor imaging (DTI) of cartilage provides a simultaneous assessment of the two principal components
arxiv
Advanced Science, EarlyView.This study utilized Ss‐STARR‐seq to construct a genome‐wide silencer map of mouse cells and elucidated the fundamental characteristics of these silencers. These silencers exist in a cell‐specific manner and exhibit unique epigenetic modifications. Through functional experiments, we also discovered that these silencers can regulate gene expression and ...
Xiusheng Zhu +12 more
wiley +1 more source
MACI Sandwich Technique With Autologous Bone Graft
Video Journal of Sports MedicineBackground: Osteochondral lesions of the knee are difficult to manage. Such lesions can be effectively treated with the matrix-induced autologous chondrocyte implantation (MACI) “sandwich” technique using autologous chondrocytes on porcine collagen ...
Tom Minas MD, MS
doaj +1 more source