Results 151 to 160 of about 278,892 (274)

Impact of Abnormal Mechanical Stress on Chondrocyte Death in Osteoarthritis. [PDF]

open access: yesMed Sci Monit
Du J   +7 more
europepmc   +1 more source

CeiTEA: Adaptive Hierarchy of Single Cells with Topological Entropy

open access: yesAdvanced Science, EarlyView.
CeiTEA, a novel hierarchical clustering algorithm based on topological entropy, effectively captures complex structures underlying data. By constructing an adaptive multi‐nary partition tree, CeiTEA reveals hierarchical structures and local diversifications, outperforming existing methods in clustering accuracy and consistency and providing the ...
Bowen Tan   +3 more
wiley   +1 more source

Repair of Bifid Sternum with Autogenous Cartilage

open access: green, 1959
DANIEL S. ROCCAFORTE   +2 more
openalex   +2 more sources

Inhibition of Heat Shock Protein 90β by Catalpol: A Potential Therapeutic Approach for Alleviating Inflammation‐Induced Cartilage Injuries in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
The schematic diagram delineates the chondroprotective effects of Ca‐bMSN in OA models. The upper portion of the diagram depicts the synthesis process of Ca‐bMSN. The lower section illustrates the post‐injection of Ca‐bMSN in joint cavity, catalpol released and subsequently mediates the reduction of oxidative stress, ECM catabolism, apoptosis, and ...
Zhenwei Zhou   +14 more
wiley   +1 more source

DNA Origami‐Based CD44‐Targeted Therapy Silences Stat3 Enhances Cartilage Regeneration and Alleviates Osteoarthritis Progression

open access: yesAdvanced Science, EarlyView.
This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv   +8 more
wiley   +1 more source

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