Results 71 to 80 of about 242,382 (269)

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Amygdala and nucleus accumbens activation are associated with treatment choice in knee osteoarthritis: an fMRI study

Arthroplasty
Background Pain in knee osteoarthritis (KOA) often shows a limited correlation with radiographic severity, complicating clinical assessment and highlighting the relevance of central pain mechanisms.
Fabiola Ojeda, Gerard Martínez-Vilavella, Laura Blanco-Hinojo, Joan Deus, Laura Tío, Jordi Monfort   +5 more
doaj   +1 more source

Cartilage Grafting

Seminars in Plastic Surgery, 2019
AbstractArthritis remains a widespread and yet unsolved therapeutic dilemma. Cartilage grafting has proven to be difficult and satisfactory results are often elusive. There are several inherent difficulties. These include both chondrocyte migration and the lack of sufficient uptake of nutrients to allow for graft survival.
Nikhil, Agrawal, Shawn, Yari, Drew, Engles, Edward M, Reece   +3 more
openaire   +3 more sources

Engineering Layered Magnetic Hydrogels for Cell Placement via Shear and Magnetic Field‐Induced Assembly

Advanced Materials, EarlyView.
Magnetic particles are organized into layered architectures by combining shear flow and magnetic fields, with the resulting structures governed by appropriate Mason numbers. The programmed assemblies provide spatial guidance for cell placement, linking field‐controlled self‐assembly, flow‐induced structuring and biological organization.
Guillermo Camacho, Jose R. Morillas, Jesús García‐Gutiérrez, Stefania Nardecchia, Óscar Martínez‐Cano, Juan de Vicente   +5 more
wiley   +1 more source

Dynamic Mechanical Loading Modulates Extracellular Vesicle Production and Cargo in Meniscus Fibrochondrocytes

Advanced Materials Interfaces, EarlyView.
Dynamic mechanical loading of outer meniscus fibrochondrocytes increases extracellular vesicle (EV) yield and alters EV composition. When applied to progenitor cells, these mechanically primed EVs modulate the expression of matrix‐related genes.
Catherine Cheung, Zizhao Li, Sung‐Han Jo, Se‐Hwan Lee, Il Keun Kwon, Jina Ko, Su Chin Heo   +6 more
wiley   +1 more source

Multifunctional Wound Dressings: Melt Electrowritten Scaffolds Combined With Phytotherapeutic Composite Hydrogels

Advanced Materials Interfaces, EarlyView.
ABSTRACT The increasing prevalence of impaired wounds, caused mainly by diabetes or aging, alongside the growing number of bacterial infections, indicates the need for alternative tissue engineering solutions. In this study, we developed novel melt electrowritten (MEW) polycaprolactone (PCL) scaffolds incorporated with an alginate (Alg)–gelatin (Gel ...
Andrada‐Ioana Damian‐Buda, Aldo Roberto Boccaccini, Irem Unalan   +2 more
wiley   +1 more source

Material Before Morphology: Substrate‐Dependent Mechanical Tuning of Radular Teeth

Advanced Materials Interfaces, EarlyView.
Substrate‐dependent material tuning in Clausilia radular teeth. Closely related taxa retain a conserved gross tooth morphology, but differ in elemental composition and mechanical properties according to feeding substrate. Rock‐associated taxa show increased Ca–Si enrichment and higher stiffness and hardness, especially in the central radular region ...
Ida Lilienthal, Bernhard Hausdorf, Stanislav N. Gorb, Wencke Krings   +3 more
wiley   +1 more source

An Imaging‐Guided, Patient‐Specific Guiding Aid (RWNGuide) for Safe and Reproducible Inner Ear Drug Delivery

Advanced Materials Technologies, EarlyView.
A patient‐specific, imaging‐guided aid enables precise and reproducible drug delivery to the inner ear. By guiding therapeutic agents directly to the round window niche, this approach reduces variability in drug localization, improves delivery safety, and addresses a critical bottleneck in inner ear therapy, offering a scalable strategy for precision ...
Yanjing Luo, Shanshan Jiang, Yimian Luo, Adele Moatti, Farnaz Matin‐Mann   +4 more
wiley   +1 more source

Pin-tract infection is an important factor associated with pin loosening during external fixation: a prospective analysis of 47 consecutive patients

Frontiers in Cellular and Infection Microbiology
BackgroundThe occurrence of pin loosening represents a common issue in the context of external fixation methodologies; nevertheless, a comprehensive investigation into the multifaceted causes of pin loosening, incorporating a multivariate analysis among ...
Yong-yi Huang, Yong-yi Huang, Yong-yi Huang, Mou-zhang Huang, Ping Zhang, Ping Zhang, Chen-sheng Song, Yu Yao, Yu-sheng Yang, Yu-sheng Yang, Liang-jie Tian, Qing-rong Lin, Qing-rong Lin, Qing-rong Lin, Ru-hao Han, Ru-hao Han, Hong-wei Xi, Bo-wei Wang, Bo-wei Wang, Nan Jiang, Nan Jiang, Yan-jun Hu, Yan-jun Hu   +22 more
doaj   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source