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Cartilage Repair: Scaffolding

2016
Regenerative scaffold-based procedures have emerged in the last years as a potential therapeutic option for the treatment of chondral and osteochondral lesions. The rationale of using a scaffold is to have a temporary 3D structure of biodegradable polymers for the growth of living cells.
KON, ELIZAVETA   +5 more
openaire   +2 more sources

Magnetic resonance imaging of cartilage and cartilage repair

Clinical Radiology, 2004
Magnetic resonance (MR) imaging of articular cartilage has assumed increased importance because of the prevalence of cartilage injury and degeneration, as well as the development of new surgical and pharmacological techniques to treat damaged cartilage.
F. Almqvist   +6 more
openaire   +3 more sources

Cartilage biology, pathology, and repair [PDF]

open access: possibleCellular and Molecular Life Sciences, 2010
Osteoarthritis is one of the most common forms of musculoskeletal disease and the most prominent type of arthritis encountered in all countries. Although great efforts have been made to investigate cartilage biology and osteoarthritis pathology, the treatment has lagged behind that of other arthritides, as there is a lack of effective disease-modifying
Daniel Umlauf   +3 more
openaire   +2 more sources

Cartilage Injury and Repair [PDF]

open access: possible, 2003
Hyaline articular cartilage is composed of water (75%), matrix (20%), and cells (5%). The cells within the matrix are termed chondrocytes. The matrix consists of 80% collagen, with collagen type II being the major component accounting for approximately 90% of the total collagen content.
Norbert Schütze   +4 more
openaire   +1 more source

Biomechanics of Cartilage Repair

2021
A detailed understanding of biomechanical characteristics of healthy articular cartilage and the effect of mechanobiology on cartilage is needed to prevent joint degeneration with biological-based treatment strategies. In vitro and in vivo experiments of cartilage repair enhanced by mechanical stress have been able to guide rehabilitation protocols ...
Benjamin B. Rothrauff   +4 more
openaire   +2 more sources

Cartilage Repair in the Hip [PDF]

open access: possible, 2014
Chondropathies of the hip, whether on the femoral head or the acetabulum, are believed to be a frequent cause of hip pain and precedent to osteoarthritis (OA). There are approximately 80,000 hip replacements performed each year in England and Wales, the majority for OA [19].
Sally Roberts   +3 more
openaire   +1 more source

The Future of Cartilage Repair

Operative Techniques in Sports Medicine, 2008
There are several cartilage regeneration procedures under development that offer potential benefits over the current techniques. We review the basics of each of these procedures and give an update on the latest clinical research involving these products.
Blanka Sharma, Brett M. Cascio
openaire   +2 more sources

Scaffolds for Articular Cartilage Repair

Annals of Biomedical Engineering, 2004
Tissue engineering of articular cartilage seeks to restore the damaged joint surface, inducing repair of host tissues by delivering repair cells, genes, or polypeptide stimulatory factors to the site of injury. A plethora of devices and materials are being examined for their potential to deliver these agents to wound sites, and to act as scaffolds for ...
Paul E. Di Cesare, Sally R. Frenkel
openaire   +2 more sources

Advances in Ankle Cartilage Repair

Clinics in Podiatric Medicine and Surgery, 2017
Repair of osteochondral lesions of the talus can be difficult. Smaller lesions respond well to simple arthroscopy and microfracture, whereas larger cystic lesions may require allograft talus replacement or ankle fusions. The lesions in between are more difficult to treat.
Kaitlyn Bernhard   +2 more
openaire   +2 more sources

The Future of Cartilage Repair

2019
Articular cartilage is a hyaline cartilage 2–4 mm thick. It is composed of 95% of dense extracellular matrix (ECM) and 5% of highly specialized cells called chondrocytes. Because of its avascular, aneural and alymphatic state, it has a limited repair potential.
Mihovil Plečko   +6 more
openaire   +2 more sources

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