Results 41 to 50 of about 91,123 (253)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Directional Filters for Cartoon + Texture Image Decomposition
We present in this article a detailed analysis and implementation of the cartoon+texture decomposition algorithm proposed in [A. Buades, J.L. Lisani, 'Directional filters for color cartoon + texture image and video decomposition', Journal of Mathematical
Antoni Buades, Jose-Luis Lisani
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Çizgi film izlemek, çocukların duyuşsal gelişimleri üzerinde büyük etkiye sahip olan olağan çocuk aktivitelerinden biridir. Bu araştırmada genel olarak çizgi filmlerin ilkokul öğrencilerinin duyuşsal özellikleri üzerindeki etkilerini ortaya koymak ...
Selma Baş Dönergüneş
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Saeed Aljohani,1 Jingyun Wang,2 Mitchell Scheiman,3 Qing-Qing Tan,4 Hongxin Xu,5 Nawaf Almutairi,1 Saleh Alshammeri1 1Department of Optometry, College of Applied Medical Science, Qassim University, Buraydah, Qassim, Saudi Arabia; 2SUNY College of ...
Aljohani S +6 more
doaj
A STEAM Experience in the Mathematics Classroom: The Role of a Science Cartoon
A multidisciplinary team collaborated on the development of a learning experience involving 10th grade students using a Science, Technology, Engineering, Arts, and Mathematics (STEAM) approach.
Daniela Marques +6 more
doaj +1 more source
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Political cartoon as a genre of political discourse
The article is devoted to the consideration of the modern political cartoons on foreign policy and socially-significant topics in Arabic and French. Political cartoon is a genre of political discourse that entered the scope of linguistic problems in the ...
Natalia M Dugalich
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Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source

