Results 91 to 100 of about 44,151 (306)
Endothelial Phenotype Evoked by Low Dose Carvedilol in Pulmonary Hypertension
Frontiers in Cardiovascular Medicine, 2018 Background: The therapeutic benefits of β-blockers are well established in left heart failure. The Pulmonary Arterial Hypertension Treatment with Carvedilol for Heart Failure [PAHTCH] study showed safety and possible benefit of carvedilol in pulmonary ...
Hoi I Cheong +12 more
doaj +1 more source
Smad3 inactivation and MiR-29b upregulation mediate the effect of carvedilol on attenuating the acute myocardium infarction-induced myocardial fibrosis in rat. [PDF]
PLoS ONE, 2013 Carvedilol, a nonselective β-adrenoreceptor antagonist, protects against myocardial injury induced by acute myocardium infarction (AMI). The mechanisms underlying the anti-fibrotic effects of carvedilol are unknown.
Jie-Ning Zhu +13 more
doaj +1 more source
Relationship between antihypertensive medications and cognitive impairment: Part II. Review of Physiology and animal studies [PDF]
, 2016 Purpose of Review There is an established association between hypertension and increased risk of poor cognitive performance and dementia including Alzheimer’s disease; however, associations between antihypertensive medications (AHM) and dementia risk are
Carlson, MC +4 more
core +1 more source
Electrospinning Using AC Electric Fields
Macromolecular Rapid Communications, EarlyView.This review covers the state‐of‐the‐art of process of alternating field electrospinning (AFES, a.k.a. AC‐electrospinning). Although tremendous progress is achieved in the development of AC‐electrospinning over the last 10 years, this technique remains uncommon. The synopses of AFES process concepts, parameters, spinneret designs, benefits and obstacles,
Andrei Stanishevsky
wiley +1 more source
Saudi Pharmaceutical Journal, 2023 Melanoma is an aggressive skin cancer. Increasing evidence has shown the role of β-adrenergic receptors in the pathogenesis of melanoma. Carvedilol is a widely used non-selective β-AR antagonist with potential anticancer activity.
Joanna Wawszczyk +3 more
doaj
Advantages in the use of carvedilol versus propranolol for the protection of cardiac mitochondrial function [PDF]
, 2004 BACKGROUND: Carvedilol is a neurohormonal antagonist of multiple action which is used in clinical practice for the treatment of congestive heart failure, mild to moderate hypertension and myocardial infarction.
Gonçalves, L +7 more
core
Cardiology, 1993 Ambulatory intra-arterial blood pressure recording provides a precise and objective method for the study of antihypertensive drugs and their effects on blood pressure. Application of this technique has shown that beta-adrenoceptor-blocking drugs are only effective during the day when the subject is active.
openaire +3 more sources
Recent Developments in the Optical Control of Adrenergic Signaling
Medicinal Research Reviews, EarlyView.ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi +4 more
wiley +1 more source
International Journal of Arrhythmia, 2020 Background Carvedilol is one of the most effective beta-blockers in reducing ventricular tachyarrhythmias and mortality in patients with heart failure.
Jongmin Hwang +12 more
doaj +1 more source
Selecting the primary endpoint in a randomized clinical trial: the ARE method [PDF]
, 2016 The decision on the primary endpoint in a randomized clinical trial is of paramount importance and the combination of several endpoints might be a reasonable choice. Gómez and Lagakos (2013) have developed a method that quantifies how much more efficient
Gómez Melis, Guadalupe +1 more
core +2 more sources