Results 41 to 50 of about 639,060 (269)
Do children receiving care and support have higher rates of school exclusion than their peers?
International Journal of Population Data ScienceThe Children, Young People and Education Committee recently held an inquiry to scrutinise the Welsh Government’s progress in delivering its Programme for Government Commitment to ‘explore radical reform of current services for children looked after and ...
Helen Hodges
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Predictive Testing for Tumor Predisposition Syndromes in Pediatric Relatives: An Asian Experience
Frontiers in Pediatrics, 2020 Approximately 10% of pediatric cancer patients possess germline pathogenic/likely pathogenic variants (PV/LPV) in known tumor predisposition genes.
Jianbang Chiang +7 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Real-Time Observation of Target Search by the CRISPR Surveillance Complex Cascade
Cell Reports, 2017 CRISPR-Cas systems defend bacteria and archaea against infection by bacteriophage and other threats. The central component of these systems are surveillance complexes that use guide RNAs to bind specific regions of foreign nucleic acids, marking them for
Chaoyou Xue +4 more
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The haemodynamic cascade [PDF]
Netherlands Heart Journal, 2013 In this issue of the Netherlands Heart Journal, Jansen et al. describe the influence stress echocardiography has on clinical decision-making in patients with mitral valve disease [1]. In 1935, Tenant and Wiggers described the sequelae of coronary occlusion [2]. From their description the ischaemic cascade has been derived. In this cascade, symptoms are
openaire +2 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Improved triplet loss for domain adaptation
IET Computer VisionA technique known as domain adaptation is utilised to address classification challenges in an unlabelled target domain by leveraging labelled source domains.
Xiaoshun Wang +2 more
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A Theoretical Comparative Study of CO2 Cascade Refrigeration Systems
Applied Sciences, 2019 The objective of this work is the comparison of the different cascade refrigeration systems with CO2 in the low-temperature circuit. A total of 18 different cascade refrigeration systems are examined including the CO2/CO2 cascade system.
Evangelos Bellos, Christos Tzivanidis
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Prevalence of polypharmacy: Comparing the status of Indian states
Indian Journal of Community and Family Medicine, 2019 Introduction: The word “poly” is Greek and means many or much. However, the term polypharmacy has been given definitions connected both to the use of more than a certain number of drugs concomitantly and to the clinical appropriateness of drug use ...
Priya Sharma, N L Gupta, H S Chauhan
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