Results 61 to 70 of about 639,060 (269)

Rumor Cascades

Proceedings of the International AAAI Conference on Web and Social Media, 2014
Online social networks provide a rich substrate for rumor propagation. Information received via friends tends to be trusted, and online social networks allow individuals to transmit information to many friends at once. By referencing known rumors from Snopes.com, a popular website documenting memes and urban legends, we track the ...
Adrien Friggeri, Lada A. Adamic, Dean Eckles, Justin Cheng   +3 more
openaire   +2 more sources

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Global polycrisis: the causal mechanisms of crisis entanglement

Global Sustainability
Multiple global crises – including the pandemic, climate change, and Russia's war on Ukraine – have recently linked together in ways that are significant in scope, devastating in effect, but poorly understood.
Michael Lawrence, Thomas Homer-Dixon, Scott Janzwood, Johan Rockström, Ortwin Renn, Jonathan F. Donges   +5 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Pairwise Similarity for Domain Adaptation

IEEE Access
The application of the domain adaptation technique enables the resolution of classification challenges in an unlabeled target domain by leveraging the labeled information from source domains.
Xiaoshun Wang, Sibei Luo
doaj   +1 more source

Integrating Two-Stage Phase Change Material Thermal Storage for Cascaded Waste Heat Recovery of Diesel-Engine-Powered Distributed Generation Systems: A Case Study

Energies, 2019
Thermal energy storage using the latent heat of phase change materials (PCMs) is a promising technique to solve the time mismatch between the availability and usage of flue gas heat in distributed generation systems (DGSs).
Dacheng Li, Yulong Ding, Peilun Wang, Shuhao Wang, Hua Yao, Jihong Wang, Yun Huang   +6 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Polycrisis in the Anthropocene: an invitation to contributions and debates

Global Sustainability
The popularity of the term polycrisis suggests a growing demand for new thinking about the world's intersecting crises, but loose and haphazard uses of the concept impede knowledge generation.
Michael Lawrence
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source