Results 71 to 80 of about 1,471,094 (304)
Factors influencing young people’s transitions from child to adult mental health services in Wales
International Journal of Population Data ScienceObjectives This presentation provides an overview of young peoples’ transitions from child to adult mental health services in Wales. Transitions are unstable times where need for support can be greatest, yet many young adults fail to qualify for ongoing
Louisa Roberts +3 more
doaj +1 more source
Real-Time Observation of Target Search by the CRISPR Surveillance Complex Cascade
Cell Reports, 2017 CRISPR-Cas systems defend bacteria and archaea against infection by bacteriophage and other threats. The central component of these systems are surveillance complexes that use guide RNAs to bind specific regions of foreign nucleic acids, marking them for
Chaoyou Xue +4 more
doaj +1 more source
Postmortem Analysis of Decayed Online Social Communities: Cascade Pattern Analysis and Prediction
, 2018 Recently, many online social networks, such as MySpace, Orkut, and Friendster, have faced inactivity decay of their members, which contributed to the collapse of these networks.
Abufouda, Mohammed
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
A Theoretical Comparative Study of CO2 Cascade Refrigeration Systems
Applied Sciences, 2019 The objective of this work is the comparison of the different cascade refrigeration systems with CO2 in the low-temperature circuit. A total of 18 different cascade refrigeration systems are examined including the CO2/CO2 cascade system.
Evangelos Bellos, Christos Tzivanidis
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Prevalence of polypharmacy: Comparing the status of Indian states
Indian Journal of Community and Family Medicine, 2019 Introduction: The word “poly” is Greek and means many or much. However, the term polypharmacy has been given definitions connected both to the use of more than a certain number of drugs concomitantly and to the clinical appropriateness of drug use ...
Priya Sharma, N L Gupta, H S Chauhan
doaj +1 more source
Jet Structure in Heavy Ion Collisions
, 2015 We review recent theoretical developments in the study of the structure of jets that are produced in ultra relativistic heavy ion collisions. The core of the review focusses on the dynamics of the parton cascade that is induced by the interactions of a ...
Blaizot, Jean-Paul, Mehtar-Tani, Yacine
core +2 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Global polycrisis: the causal mechanisms of crisis entanglement
Global SustainabilityMultiple global crises – including the pandemic, climate change, and Russia's war on Ukraine – have recently linked together in ways that are significant in scope, devastating in effect, but poorly understood.
Michael Lawrence +5 more
doaj +1 more source