Efficient identification of patients eligible for clinical studies using case-based reasoning on Scottish Health Research register (SHARE). [PDF]
Shi W, Kelsey T, Sullivan F.
europepmc +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Development of a Casting Process Database for Rapid Process Design Using Case-Based Reasoning. [PDF]
Zhou C +6 more
europepmc +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
A fuzzy ontology-based case-based reasoning system for stomach dystemperament in Persian medicine. [PDF]
Shojaee-Mend H +2 more
europepmc +1 more source
Improving Prototypical Parts Abstraction for Case-Based Reasoning Explanations Designed for the Kidney Stone Type Recognition [PDF]
Daniel Flores-Araiza +7 more
openalex +1 more source
A CASE BASED REASONING ARCHITECTURE AND COMPONENT BASED MODEL FOR GREEN IS IMPLEMENTATION AND DIFFUSION IN ORGANISATION [PDF]
Bokolo Anthony +1 more
openalex +1 more source
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Enhance health evidence quality in classification tasks: A triangulation approach utilizing case-based reasoning and process features. [PDF]
Guo R +4 more
europepmc +1 more source

