Results 61 to 70 of about 29,109,104 (283)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Journal of Information and Technology, 2019 Kebutuhan akan informasi tentang penyakit sapi saat ini sangatlah dibutuhkan, hal yang biasanya terjadi pada daerah yang jauh dari pemukiman salah satunya para peternak sapi yang berlokasi di pedesaan yang jauh dari teknologi kurangnya jumlah para ahli ...
Rachmania Indah Permata Sari +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
International Journal of Interactive Multimedia and Artificial Intelligence, 2008 This paper shows how we have developed a video game for Nintendo DS in order to play Mus, one of the most popular Spanish card games, thereby we considered designing a video game would be an interesting way of applying our acquired knowledge about ...
Sergio Redondo +2 more
doaj
The Development and Evaluation of a Clinical Reasoning Case for Second-Year Medical Students
MedEdPORTALIntroduction Clinical reasoning is a cornerstone of diagnostic and therapeutic decision-making, yet it is infrequently taught in preclinical medical education and is often taught implicitly.
Millie C. Kirchberg +2 more
doaj +1 more source
SISTEM BERBASIS KASUS UNTUK MENENTUKAN TINGKAT RESIKO KOMPLIKASI AKIBAT DIABETES MELITUS
Multitek Indonesia, 2017 Sistem berbasis kasus untuk menentukan tingkat resiko komplikasi akibat diabetes mellitus ini merupakan suatu sistem pakar yang dirancang sebagai alat bantu untuk mendiagnosis penyakit komplikasi akibat diabetes mellitus khusus pada penderita diabetes ...
Lukman Effendi
doaj +1 more source
CBRR Model for Predicting the Dynamics of the COVID-19 Epidemic in Real Time
Mathematics, 2020 Because of the lack of reliable information on the spread parameters of COVID-19, there is an increasing demand for new approaches to efficiently predict the dynamics of new virus spread under uncertainty.
Victor Zakharov +3 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
RANCANGAN CASE-BASED REASONING MENGGUNAKAN SORENSON COEFFICIENT
Jurnal Informatika, 2013 Penalaran berbasis kasus (Case-Based Reasoning) untuk melakukan diagnosa penyakit berdasarkan gejala-gejala yang ada. Proses diagnosa dilakukan dengan cara memasukkan kasus baru (target case) yang berisi gejala-gejala penyakit yang akan didiagnosa ...
Murien Nugraheni
doaj