Results 121 to 130 of about 21,521,804 (362)
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Systematic investigation on the effects of human exposure to environmental pollution using scientific methodology only began in the 20th century as a consequence of several environmental accidents followed by an unexpected mortality increase above ...
André Paulo Afonso de +6 more
doaj
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Inorganic materials in industrial processes [PDF]
Although inorganic materials represent a small number to the extreme number of the organic ones, they play a number of crucial roles in several processes of industrial interest.
Demadis, Konstantinos D.
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Fatores associados à ideação suicida na comunidade: um estudo de caso-controle
Este estudo tem como objetivo identificar variáveis associadas à ideação suicida ao longo dos últimos 12 meses, na cidade de Campinas, São Paulo, Brasil.
Viviane Franco da Silva +5 more
doaj
Comprasion of Acnea prevalence in melasmatic and non-melasmatic (with and without Hirsutism) more than 27 years old woman [PDF]
Objective: Melasma is the adventitious increase of skin pigments that is created slowly and with a symmetric form.Acne is a chronic inflammatory disease of the pilosebaceous units.Because of high prevalence of melasma in Ardabils women & because of ...
صادقیه اهری, سعید +2 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Background Psychological stress is linked to elevated salivary cortisol levels, potentially worsening periodontitis by exacerbating inflammation. This study examines the impact of stress on cortisol levels in periodontitis patients, aiming to explore ...
Mozaffer Rahim Hingorjo +4 more
doaj +1 more source

