Results 111 to 120 of about 2,144,056 (301)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Does case management improve outcomes for people with schizophrenia? [PDF]

open access: yes
The Australian and New Zealand clinical practice guidelines recommend intensive case management for people with first-episode psychosis or an acute relapse of schizophrenia.
Alana Shepherd   +4 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Corrigendum to “Coronavirus Disease-19: The First 7,755 Cases in the Republic of Korea” [Osong Public Health Res Perspect 2020;11(2):85–90] [PDF]

open access: yesOsong Public Health and Research Perspectives, 2020
COVID-19 National Emergency Response Center, Epidemiology and Case Management Team   +1 more
doaj   +1 more source

Case Management Interviews and the Return to Work of Disabled Employees [PDF]

open access: yes
This study measures the effect of case management interview (CMI) on 1,000 long-term sick-listed employees’ probability of returning to work. In contrast to previous studies, we use instrumental variables to correct for selection effects in CMI.
Anders Holm, Jan Høgelund
core  

Moving Beyond the Client Role: Helping Human Service Organizations Identify Program Participant’s Assets [PDF]

open access: yes, 2004
Human service agencies have traditionally provided services to a population considered in need of those services. Program participants are often seen solely as passive recipients of food, housing, health care, case management, etc.
Figueroa, Sandra   +2 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The Dairy Case Management Program: Does It Mooove More Milk? [PDF]

open access: yes
Livestock Production/Industries, M31, Q13,
Chung, Chanjin   +2 more
core   +1 more source

An Assessment of the Colorado Refugee Services Program With Recommendations for Improvement [PDF]

open access: yes, 2005
Summarizes findings on the structure and services of the state's refugee resettlement program from document reviews, interviews, and focus group discussions.

core  

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