Results 51 to 60 of about 301,273 (141)

RNF43 ubiquitinates and degrades phosphorylated E-cadherin by c-Src to facilitate epithelial-mesenchymal transition in lung adenocarcinoma

BMC Cancer, 2019
Background In epithelial cells, tyrosine kinases induce tyrosine phosphorylation and ubiquitination of the E-cadherin complex, which is responsible for the epithelial-mesenchymal transition (EMT). However, the precise mechanisms remain unclear.
Yunfeng Zhang, Liangzhang Sun, Xiao Gao, Aining Guo, Yan Diao, Yang Zhao   +5 more
doaj   +1 more source

Drozitumab, a Human Antibody to Death Receptor 5, Has Potent Antitumor Activity against Rhabdomyosarcoma with the Expression of Caspase-8 Predictive of Response [PDF]

, 2011
Zhigang Kang, Junjie Chen, Yunkai Yu, Bo Li, Shi‐Yong Sun, Baolin Zhang, Liang Cao   +6 more
openalex   +1 more source

Integrated In Silico and In Vivo evaluation of Cassytha filiformis: Molecular insights into caspase-3/8 binding and wound healing effect

Pharmacological Research - Modern Chinese Medicine
Background: Cassytha filiformis is a parasitic vine traditionally used in Chinese traditional medicine (CTM) for its anti-inflammatory, detoxifying, and wound-healing properties.
Soosamma John, Nisha Shri Chengamaraju, Navya A S, Agasa Ramu Mahesh, Bincy Raj   +4 more
doaj   +1 more source

[Endoplasmic reticulum stress enhances tumor necrosis factor-α expression in rat Kupffer cells to trigger hepatic stellate apoptosis cell through TNFR/caspase-8 pathway].

, 2020
Hong Gao, Nan Wen, Xuesong Xu, Guoqing Hong, Xing Lai   +4 more
openalex   +2 more sources

Effects of 8-week Exercise on Bcl-2, Bax, Caspase-8, Caspase-3 and HSP70 in Mouse Gastrocnemius Muscle [PDF]

, 2010
Ki-Bum Kim, Yong An Kim, Jung-Jun Park
openalex   +1 more source

Phosphorylation of caspase-8 by RSKs via organ-constrained effects controls the sensitivity to TNF-induced death

Cell Death Discovery
Caspase-8 (Casp8) serves as an initiator of apoptosis or a suppressor of necroptosis in context-dependent manner. Members of the p90 RSK family can phosphorylate caspase-8 at threonine-265 (T265), which can inactivate caspase-8 for bypassing caspase-8 ...
Peng He, Tingting Ai, Muzhen Qiao, Zhang-Hua Yang, Jiahuai Han   +4 more
doaj   +1 more source

Caspase-8: Clipping off RIG-I Signaling [PDF]

, 2011
Susanne Roth, Jürgen Ruland
openalex   +1 more source

Fanconi anemia type C–deficient hematopoietic cells are resistant to TRAIL (TNF-related apoptosis-inducing ligand)-induced cleavage of pro-caspase-8 [PDF]

, 2004
Uwe Platzbecker, Peter Kurre, Philippe Guardiola, Jessica Ward, Jerald P. Radich, Hans‐Peter Kiem, H. Joachim Deeg   +6 more
openalex   +1 more source

Fas Ligand in Pemphigus Sera Induces Keratinocyte Apoptosis through the Activation of Caspase-8 [PDF]

, 2003
Mario Puviani, Alessandra Marconi, Carlo Pincelli, Emanuele Cozzani   +3 more
openalex   +1 more source

Supplementary Figure Legends 1-6 from MUC1 Oncoprotein Blocks Death Receptor–Mediated Apoptosis by Inhibiting Recruitment of Caspase-8 [PDF]

, 2023
Naoki Agata, Rehan Ahmad, Takeshi Kawano, Deepak Raina, Surender Kharbanda, Donald Küfe   +5 more
openalex   +1 more source