Results 121 to 130 of about 16,586,228 (338)

From Exciton Dynamics to Cell Fate: A Carbon Dot Based NIR Photocatalytic Platform for Pyroptosis via Self‐Trapped Excitons

Advanced Functional Materials, EarlyView.
A facile and effective method to boost NIR light induced photocatalysis based on nontoxic NIR emissive carbon dots (nir‐CDs) via Self‐trapped excitons, showing that both O2− • and •OH can be generated from nir‐CDs under NIR laser irradiation. Abstract Near‐infrared (NIR) light‐triggered photocatalytic therapy remains a critical challenge in efficient ...
Qingcheng Wang, Quansheng Cheng, Bingzhe Wang, Tesen Zhang, Yupeng Liu, Ruifeng Zheng, Shi Chen, Guichuan Xing, Songnan Qu   +8 more
wiley   +1 more source

A short caspase-3 isoform inhibits chemotherapy-induced apoptosis by blocking apoptosome assembly.

PLoS ONE, 2011
Alternative splicing of caspase-3 produces a short isoform caspase-3s that antagonizes caspase-3 apoptotic activity. However, the mechanism of apoptosis inhibition by caspase-3s remains unknown.
Frédérique Végran, Romain Boidot, Eric Solary, Sarab Lizard-Nacol   +3 more
doaj   +1 more source

Dentatorubral Pallidoluysian Atrophy (DRPLA) Protein Is Cleaved by Caspase-3 during Apoptosis [PDF]

, 1997
Toshiyuki Miyashita, Yuko Okamura-Oho, Yasuyuki Mito, Shigeo Nagafuchi, Masao Yamada   +4 more
openalex   +1 more source

Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation.

Journal of Clinical Investigation, 2014
Caspase-3-mediated spontaneous death in neutrophils is a prototype of programmed cell death and is critical for modulating physiopathological inflammatory responses; however, the underlying regulatory pathways remain ill defined.
F. Loison, Haiyan Zhu, Kutay Karatepe, A. Kasorn, Peng Liu, K. Ye, Jiaxi Zhou, Shannan Cao, Haiyan Gong, D. Jenne, E. Remold-O’Donnell, Yuanfu Xu, Hongbo R. Luo   +12 more
semanticscholar   +1 more source

Synthetic Bilirubin‐Based Nanomedicine Protects Against Renal Ischemia/Reperfusion Injury Through Antioxidant and Immune‐Modulating Activity

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan, Hyunjin Kim, Bomin Kim, Honglin Piao, Joon Young Jang, Tae Kyeom Kang, Wook‐Bin Lee, Dohyeon Kim, Seunghyun Jo, Duckhyang Shin, Sharif MD Abuzar, Myung L. Kim, Jaeseok Yang, Sangyong Jon   +13 more
wiley   +1 more source

Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease [PDF]

, 1998
King-Teh Lin, Jiyan Xue, Marie C. Lin, Eric G. Spokas, Frank F. Sun, Patrick Y.-K. Wong   +5 more
openalex   +1 more source

Caspase 3 promotes surviving melanoma tumor cell growth after cytotoxic therapy

Journal of Investigative Dermatology, 2014
Metastatic melanoma often relapses despite cytotoxic treatment, so the understanding of melanoma tumor repopulation is crucial to improving our current therapies.
Anne L Donato, Qian Huang, Xinjian Liu, Fang Li, Mary A Zimmerman, Chuan-Yuan Li   +5 more
semanticscholar   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Bcl-2 expression in target cells leads to functional inhibition of caspase-3 protease family in human NK and lymphokine-activated killer cell granule-mediated apoptosis. [PDF]

, 1997
Claire Renvoizé, R. Beerli Roger, Nathalie Moulian, Jacques Bertoglio, J Bréard   +4 more
openalex   +1 more source

Carbon‐Based Flexible Electrode for Efficient Electrochemical Generation of Reactive Chlorine Species in Tumor Therapy

Advanced Healthcare Materials, EarlyView.
A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang, Zhaoyu Chen, Ruihao Yang, Ziga Luogu, Qian Ren, Hao Hu, Kaixin Wang, Senlin Li, Changlin Deng, Meng Li, Lu Zheng   +10 more
wiley   +1 more source