Results 91 to 100 of about 4,575,594 (299)
The Effect of Hepcidin on Cardiac Ischemia-Reperfusion Injury
Journal of Investigative Surgery, 2020 Background/aim: Hepcidin is the main hormone in the regulation of iron metabolism which is also released from the heart. The aim of our study was to investigate the effects of hepcidin on the cardiac ischemia-reperfusion injury. Materials and methods: In
Atilla Bayraktar +5 more
doaj +1 more source
Caspase-9 cleavage: do you need it
, 2007 Caspase-9 which is activated by association with the Apaf-1 apoptosome complex cleaves and activates the downstream effector caspases-3 and -7, thereby executing the caspase-cascade and cell death programme.
Davina Twiddy (7582331) +1 more
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Advanced Engineering Materials, EarlyView.Selenium was incorporated into a sol–gel‐derived bioactive glass to enable sustained therapeutic ion release. The selenium‐containing glass preserved bioactivity while selectively inducing cytotoxicity in osteosarcoma cells and maintaining osteoblastic viability.
Breno Rocha Barrioni +7 more
wiley +1 more source
Molecules, 2016 Pien Tze Huang (PZH) is a well-known traditional Chinese formulation and has long been used as an alternative remedy for cancers in China and Southeast Asia.
Yong Fu +7 more
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HCV-induced caspase-8 activity modulates caspase-9 cleavage.
, 2014 Huh7.5.1 cells were infected with HCVcc in the absence or presence of caspase-8 inhibitor (20 µM) for 72 h before harvest. The expression levels of truncated Bid (t-Bid) and cleaved caspase-9 were analyzed by Western blotting with antibodies specific to ...
Eui Ju Park (578043) +12 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim +5 more
wiley +1 more source
Caspase-independent role of Apaf1 in T cell activation.
, 2018 LN cells from immunized Apaf1f/f-OTII or Lck-Cre-Apaf1f/f -OTII mice were stimulated with indicated doses of OVA or anti-CD3ε antibody in the presence or absence of z-VAD-fmk (z-VAD) for 48 hours.
Yasunobu Miyake (522605) +5 more
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Chromosomal Instability Drives Glioblastoma Heterogeneity and Therapeutic Opportunities
Advanced Science, EarlyView.ABSTRACT Glioblastoma, the most aggressive and lethal form of brain cancer, is defined by profound genomic instability, with Chromosomal Instability (CIN) playing a central role in driving tumor progression, therapy resistance, and poor prognosis. CIN is characterized by numerical and structural alterations, is driven by mechanisms such as mitotic ...
Amarnath Pal +3 more
wiley +1 more source
Drug Design, Development and Therapy, 2020 Chen H, Dong Y, He X, Li J, Wang J. Drug Des Devel Ther. 2018;12:823–836. The authors have advised Figure 11D on page 833 is incorrect. Due to an error at the time of figure assembly Figure 10D and Figure 11D were duplicated.
Chen H, Dong Y, He X, Li J, Wang J
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Potency of mycotoxin binders on MDA level, expressions of caspase 9 and caspase 3 in the uterus of mice exposed to zearalenone [PDF]
Iraqi Journal of Veterinary Sciences, 2017 This study examined effect of mycotoxin binder administered to female mice exposed to zearalenon on apoptosis incidence by observe at MDA, Caspase 9 and 3 levels in mice uterus.
A. Samik , E. Safitri
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