Results 201 to 210 of about 262,302 (283)

FGFR4-specific CAR-T cells with inducible caspase-9 suicide gene as an approach to treat rhabdomyosarcoma. [PDF]

open access: yesCancer Gene Ther
Xiao W   +10 more
europepmc   +1 more source

Caspase-9 Transduction Overrides the Resistance Mechanism against p53-mediated Apoptosis in U-87MG Glioma Cells

open access: hybrid, 2001
Nobusada Shinoura   +4 more
openalex   +1 more source

Apoptosis induction in renal cell carcinoma by TRAIL and γ-radiation is impaired by deficient caspase-9 cleavage [PDF]

open access: hybrid, 2003
U. Ramp   +6 more
openalex   +1 more source

Neuronal FGF13 Inhibits Mitochondria‐Derived Damage Signals to Prevent Neuroinflammation and Neurodegeneration in a Mouse Model of Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
This study elucidates a novel role of FGF13 in manipulating neuronal fate via mitochondrial transfer. FGF13 is identified as a mitochondria‐stabilizing protein by interacting with mitochondrial proteins. Under stress, the decrease of neuronal FGF13 fails to retain mitochondria within the cytoplasm, leading to the release of damaged mitochondria to ...
Nanshan Song   +15 more
wiley   +1 more source

Caspase-9 Is a Positive Regulator of Osteoblastic Cell Migration Identified by diaPASEF Proteomics. [PDF]

open access: yesJ Proteome Res
Říhová K   +9 more
europepmc   +1 more source

Inducible caspase-9 suicide gene under control of endogenous oct4 to safeguard mouse and human pluripotent stem cell therapy. [PDF]

open access: yesMol Ther Methods Clin Dev, 2022
Liu Y   +15 more
europepmc   +1 more source

Targeted Penetrating Motif Engineering of BH3 Mimetic: Harnessing Non‐Canonical Amino Acids for Coinhibition of MCL‐1 and BCL‐xL in Acute Myeloid Leukemia

open access: yesAdvanced Science, EarlyView.
A structure‐guided peptide derived from a non‐canonical amino acid library simultaneously targets MCL‐1 and BCL‐xL to overcome apoptotic resistance in acute myeloid leukemia. Fused with a CXCR4‐binding motif, the engineered peptide exhibits selective intracellular delivery and potent in vivo efficacy, offering a promising therapeutic strategy against ...
Zhe Wang   +11 more
wiley   +1 more source

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