Results 231 to 240 of about 301,365 (321)

Saponins of Marsdenia Tenacissima promotes apoptosis of hepatocellular carcinoma cells through damaging mitochondria then activating cytochrome C/Caspase-9/Caspase-3 pathway. [PDF]

J Cancer, 2022
Jiang XP, Jin S, Shao W, Zhu L, Yan S, Lu J.   +5 more
europepmc   +1 more source

gamma-Tocopheryl quinone induces apoptosis in cancer cells via caspase-9 activation and cytochrome c release [PDF]

, 2003
Gabriella Calviello
openalex   +1 more source

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

Advanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang, Pengzhan He, Cheng Liu, Xin Chen, Yilin Tan, Rui Qu, Yan Zhang, Zhou Li, Tailang Yin, Zhinang Yin   +9 more
wiley   +1 more source

Robust In Vitro and In Vivo Immunosuppressive and Anti-inflammatory Properties of Inducible Caspase-9-mediated Apoptotic Mesenchymal Stromal/Stem Cell. [PDF]

Stem Cells Transl Med, 2022
Romecín PA, Vinyoles M, López-Millán B, de la Guardia RD, Atucha NM, Querol S, Bueno C, Benitez R, Gonzalez-Rey E, Delgado M, Menéndez P.   +10 more
europepmc   +1 more source

Cyclic-AMP Inhibits Nitric Oxide-Induced Apoptosis in Human Osteoblast: The Regulation of Caspase-3, -6, -9 and the Release of Cytochrome c in Nitric Oxide-Induced Apoptosis by cAMP.

, 2001
Han‐Jung Chae, Soo‐Wan Chae, Nyeon‐Hyoung An, Jong-Hwan Kim, Chulwon Kim, Sim-Keun Yoo, Hong‐Hee Kim, Zang-Hee Lee, Hyung‐Ryong Kim   +8 more
openalex   +2 more sources

Perforin‐dependent activation‐induced cell death acts through caspase 3 but not through caspases 8 or 9 [PDF]

, 2003
Liane Chen, Minna Woo, Razqallah Hakem, Richard G. Miller   +3 more
openalex   +1 more source

Irisin Attenuates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension via Ubiquitin‐Mediated Regulation of ENO1

Advanced Science, EarlyView.
Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun, Yong‐Bing Wang, Jing Huang, Run‐Wei Deng, Hui‐Yu He, Lei Gao, Xuan Gao, You‐Li Fan, Yan Cong, Yao‐Lei Guo, Yi‐Qiang Chen, Gui‐Jia Wang, Shao‐Hong Fang, Xia Gu, Bo Yu, Bing‐Xiang Wu   +15 more
wiley   +1 more source

FGFR4-specific CAR-T cells with inducible caspase-9 suicide gene as an approach to treat rhabdomyosarcoma. [PDF]

Cancer Gene Ther
Xiao W, Xu L, Wang J, Yu K, Xu B, Que Y, Zhao J, Pan Q, Gao C, Zhou P, Zhang X.   +10 more
europepmc   +1 more source

lncRNA PROX1-AS1 mediates the migration and invasion of placental trophoblast cells via the miR-211-5p/caspase-9 axis. [PDF]

Bioengineered, 2021
Tang D, Geng L, Ma J.
europepmc   +1 more source

Cytochrome c Release Is Upstream to Activation of Caspase-9, Caspase-8, and Caspase-3 in the Enhanced Apoptosis of Anaplastic Thyroid Cancer Cells Induced by Manumycin and Paclitaxel

, 2001
J. Pan
openalex   +1 more source