Results 161 to 170 of about 526,882 (310)

Induction of apoptosis by 2,3-dehydrosilybinviaa caspase-dependent pathway in human HeLa cells [PDF]

, 2014
Byoung Ok Cho, Yangkang So, Chang Hyun Jin, Myung Woo Byun, Kwon‐Il Seo, Kisung Ko, Myoung Sook Chun, Il Yun Jeong   +7 more
openalex   +1 more source

RSV temporally reprograms apoptosis and pyroptosis to balance immune evasion and replication. [PDF]

Sci Adv
Liu C, Zhou H, Li J, Meng Y, Wang J, He M, Wang W, Li Z, Qin Y, Chen M.   +9 more
europepmc   +1 more source

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, EarlyView.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

Can Environmental Enrichment Mitigate Cell Apoptosis in the Central Nervous System Under Adverse Health Conditions? A Systematic Review. [PDF]

Clin Transl Sci
de Sousa Fernandes MS, Ferreira DJS, Yagin FH, Badicu G, Santos GCJ, Guedes MCS, Souto FO, Ardigò LP.   +7 more
europepmc   +1 more source

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

Arsenic Trioxide Selectively Induces Early and Extensive Apoptosis via the APO2/Caspase-8 Pathway Engaging the Mitochondrial Pathway in Myeloma Cells with Mutant p53 [PDF]

, 2003
Cagla Akay
openalex   +1 more source

LPS-induced structural reorganization and polymerization drive noncanonical inflammasome activation. [PDF]

Sci Adv
Wang C, Lacey P, Tian T, Teran E, Liaqat M, Shivcharan S, Shumba P, He J, Rathinam VA, Wysocki VH, Ruan J.   +10 more
europepmc   +1 more source

Caspase functions in cell death and disease.

Cold Spring Harbor Perspectives in Biology, 2013
D. Mcilwain, T. Berger, T. Mak
semanticscholar   +1 more source

Seipin‐Mediated Lipid Droplet Formation in Cardiomyocytes Ameliorates Cardiac Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Lipid droplets (LDs) protect the heart against lipotoxicity in cardiac ischemia/reperfusion (I/R) injury; however, they are insufficient to prevent cardiomyocyte death. Seipin plays a central role in the insufficient formation of LDs, subsequent lipotoxicity, and myocardial injury during cardiac I/R injury.
Changyun Liu, Junxia Zhang, Yusi Chen, Geng Shen, Yufei Han, Zihao Zhou, Jinxuan Chen, Xuya Kang, Huilin Qu, Jiaxin Duanmu, Haibao Shang, Yingjia Li, Wei Huang, Yan Zhang   +13 more
wiley   +1 more source

Pyroptosis in Peripheral Neuropathy: From Molecular Mechanisms to Therapeutic Targeting. [PDF]

CNS Neurosci Ther
Wei J, Liuyuan M, Ye Z, Wang X, Zhou X, Shan Y, He C, Zhu C, Zhou C, Bao J, Zhang Y, Chen G.   +11 more
europepmc   +1 more source