Results 261 to 270 of about 514,126 (359)

RSL3 promotes PARP1 apoptotic functions by distinct mechanisms during ferroptosis. [PDF]

Cell Mol Biol Lett
Chen D, Xie F, Mo Y, Qin D, Zheng B, Chen L.   +5 more
europepmc   +1 more source

Mechanisms of caspase activation and inhibition during apoptosis.

Molecules and Cells, 2002
Yigong Shi
semanticscholar   +1 more source

A Redox‐Active and Electroactive Hydrogel Enabled by an Integrated PEDOT@PMOF Nanofiller for Post‐Infarct Myocardial Repair

Advanced Science, EarlyView.
An integrated nanoparticle PEDOT@PMOF is constructed as a redox‐active nanozyme and electroactive nanofiller in a cell‐affinity hydrogel platform for acute MI treatment. It is demonstrated that MOF‐based nanozymes have good catalytic ability, and the incorporation of PEDOT increases the conductivity.
Shuyi He, Linyu Long, Wenqi Liu, Zhicun Wang, Xiaofeng Wu, Li Yang, Yunbing Wang   +6 more
wiley   +1 more source

Elucidating molecularly stratified single agent, and combination, therapeutic strategies targeting MCL1 for lethal prostate cancer. [PDF]

Nat Commun
Jiménez-Vacas JM, Westaby D, Figueiredo I, De Haven Brandon A, Padilha A, Yuan W, Seed G, Bogdan D, Gurel B, Bertan C, Miranda S, Lambros M, Montero-Hidalgo AJ, Coleman I, Yu IPL, Buroni L, Zeng W, Neeb AJ, Welti J, Rekowski J, Paravati R, Gabel F, Pandell N, Ferreira A, Crespo M, Riisnaes R, Das S, Taylor J, Waldron N, Hobern E, Valenti M, Ning J, Bernett I, Liodaki K, Persse T, Galipeau P, Wilkinson S, Trostel SY, Karzai F, Chau CH, Beatson EL, Zhang X, Klumpp-Thomas C, Varkaris A, Luque RM, Swain A, Raynaud F, Lack NA, Thomas CJ, Ha G, Figg WD, Bezzi M, Sowalsky AG, Nelson PS, Carreira S, Balk SP, de Bono JS, Sharp A.   +57 more
europepmc   +1 more source

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

Science, 2013
Jon A. Hagar, D. Powell, Y. Aachoui, R. Ernst, Edward A. Miao   +4 more
semanticscholar   +1 more source

Restoring NK Cell Cytotoxicity Post‐Cryopreservation via Synthetic Cells

Advanced Science, EarlyView.
In this study, it is shown that 1‐day co‐culture with activated T cells or IL‐2‐presenting synthetic cells significantly enhances NK cell motility and cytotoxicity in 2D and 3D. Notably, synthetic cells restore the impaired cytotoxic function of cryopreserved NK and CAR‐NK cells in 3D.
Xiangda Zhou, Sijia Zhang, Wenjuan Yang, Susanne Gonder, Zeinab Sadjadi, Nils Piernitzki, Alina Moter, Shulagna Sharma, Anne Largeot, Nadja Küchler, Lea Kaschek, Gertrud Schäfer, Eva C. Schwarz, Hermann Eichler, Evelyn Ullrich, Heiko Rieger, Oskar Staufer, Jérôme Paggetti, Etienne Moussay, Markus Hoth, Bin Qu   +20 more
wiley   +1 more source

Combined Hesperidin and Doxorubicin Treatment Induces Apoptosis and Modulates Inflammatory Cytokines in HeLa Cervical Cancer Cells. [PDF]

Int J Mol Sci
Özdemir İ, Afşin Y, Tuncer MC, Öztürk Ş.   +3 more
europepmc   +1 more source

From Bench to Bedside: Emerging Paradigms in CAR‐T Cell Therapy for Solid Malignancies

Advanced Science, EarlyView.
This review discusses emerging paradigms in CAR‐T cell therapy for solid tumors, emphasizing strategies to overcome therapeutic barriers through synthetic biology, immune engineering, and combinatorial approaches. It highlights advancements in logic gating, modulation of the immune microenvironment, and innovative cell designs, providing valuable ...
Yang Chen, Ran Ren, Lirong Yan, Yu Zhou, Ruokai Sun, Huicong Song, Hongfei Yan, Yongsheng Li   +7 more
wiley   +1 more source

Regulation of pyroptosis by natural products in atherosclerosis: mechanisms and therapeutic potential. [PDF]

Front Pharmacol
Shi N, Wei L, Wang H, Sun S, Yang J, Zhou Y.   +5 more
europepmc   +1 more source

A caspase 8-cathepsin B protease cascade contributes to bile salt-induced hepatocyte apoptosis

, 1998
William A. Faubion, Patricia J. Roberts, Steve F. Bronk, L. B. Agellon, G. J. Gores   +4 more
openalex   +1 more source