Results 151 to 160 of about 24,063,457 (338)

Role of Pyroptosis in Respiratory Diseases and its Therapeutic Potential

open access: yesJournal of Inflammation Research, 2022
Jingjing Liu,1– 3 Guoqing Fan,1– 3 Ningning Tao,4 Tieying Sun1,2 1Department of Respiratory Medicine and Critical Care, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing ...
Liu J, Fan G, Tao N, Sun T
doaj  

Fas/Apo [Apoptosis]-1 and Associated Proteins in the Differentiating Cerebral Cortex: Induction of Caspase-Dependent Cell Death and Activation of NF-κB [PDF]

open access: hybrid, 1999
Zulfiqar F. Cheema   +5 more
openalex   +1 more source

From Exciton Dynamics to Cell Fate: A Carbon Dot Based NIR Photocatalytic Platform for Pyroptosis via Self‐Trapped Excitons

open access: yesAdvanced Functional Materials, EarlyView.
A facile and effective method to boost NIR light induced photocatalysis based on nontoxic NIR emissive carbon dots (nir‐CDs) via Self‐trapped excitons, showing that both O2− • and •OH can be generated from nir‐CDs under NIR laser irradiation. Abstract Near‐infrared (NIR) light‐triggered photocatalytic therapy remains a critical challenge in efficient ...
Qingcheng Wang   +8 more
wiley   +1 more source

Inhibition of caspase pathways limits CD4+ T cell loss and restores host anti-retroviral function in HIV-1 infected humanized mice with augmented lymphoid tissue

open access: yesRetrovirology
The study of HIV infection and pathogenicity in physical reservoirs requires a biologically relevant model. The human immune system (HIS) mouse is an established model of HIV infection, but defects in immune tissue reconstitution remain a challenge for ...
Alex J. Holloway   +8 more
doaj   +1 more source

Engineering Highly Cellularized Living Materials via Mechanical Agitation

open access: yesAdvanced Functional Materials, EarlyView.
A mechanical agitation strategy is developed to engineer highly cellularized living materials, achieving cell densities of up to 1 billion cells per milliliter. By precisely tuning properties such as stiffness and toughness in blood clots, the approach is validated in both in vitro and in vivo studies.
Aram Bahmani   +9 more
wiley   +1 more source

The Regulation of Anoikis: MEKK-1 Activation Requires Cleavage by Caspases [PDF]

open access: bronze, 1997
Michael H. Cardone   +4 more
openalex   +1 more source

Synthetic Bilirubin‐Based Nanomedicine Protects Against Renal Ischemia/Reperfusion Injury Through Antioxidant and Immune‐Modulating Activity

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan   +13 more
wiley   +1 more source

Identification of CARDIAK, a RIP-like kinase that associates with caspase-1 [PDF]

open access: bronze, 1998
Margot Thome   +6 more
openalex   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

open access: yesAdvanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy