Advanced Functional Materials, EarlyView.The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen +13 more
wiley +1 more source
Tissue Inhibitor of Metalloproteinase–3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells [PDF]
, 2018 Over expression of Tissue Inhibitor of Metalloproteinases-3 (TIMP-3) in vascular smooth muscle cells (VSMCs) induces apoptosis and reduces neointima formation occurring after saphenous vein interposition grafting or coronary stenting.
Baker, Andrew H. +5 more
core +4 more sources
Caspase-9 Activation and Caspase Cleavage of tau in the Alzheimer's Disease Brain
Neurobiology of Disease, 2002 Accumulating evidence supports a role for the activation of proteolytic enzymes, caspases, in the Alzheimer's disease (AD) brain. Neurons committed to apoptosis may do so through a mitochondrial pathway employing caspase-9 or through an alternative ...
Troy T. Rohn +5 more
doaj +1 more source
Caspases‐3 and ‐7 are activated in goniothalamin‐induced apoptosis in human Jurkat T‐cells [PDF]
, 1999 Salmaan H. Inayat‐Hussain +6 more
openalex +1 more source
Plasma‐Treated Hydrogel for Combined RONS and Chemotherapy Delivery: A Proof‐of‐Concept In Ovo
Advanced Functional Materials, EarlyView.This study explores plasma‐treated hydrogels (PTH) as a new way to deliver both reactive oxygen and nitrogen species and chemotherapy (Doxorubicin) directly to tumors. In ovo tests show effects after a single dose, especially in osteosarcoma tumors. Tumor weight decrease, and a resistance‐related protein is reduced.
Milica Živanić +9 more
wiley +1 more source
Immunohistochemical Analysis of Interleukin-1β–Converting Enzyme/Ced-3 Family Protease, CPP32/Yama/Caspase-3, in Hodgkin's Disease [PDF]
, 1997 Mukesh Chhanabhai +5 more
openalex +1 more source
Advanced Functional Materials, EarlyView.Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro +7 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang +9 more
wiley +1 more source
Bcr-Abl Exerts Its Antiapoptotic Effect Against Diverse Apoptotic Stimuli Through Blockage of Mitochondrial Release of Cytochrome C and Activation of Caspase-3 [PDF]
, 1998 Gustavo P. Amarante‐Mendes +6 more
openalex +1 more source
Inhibition effects of paeonol on mice bearing EMT6 breast cancer through inducing rumor cell apoptosis [PDF]
, 2014 Paeonol, a phenolic component from the root bark of Paeonia moutan, has been identified to possess antitumor effects on mice bearing EMT6 breast cancer in our previous studies. However, the underlying mechanisms remain unknown.
Dong, Hang +6 more
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