Results 121 to 130 of about 459,603 (305)

Androgen and estrogen receptor expression in the developing human penis and clitoris. [PDF]

, 2020
To better understand how the human fetal penis and clitoris grows and remodels, we undertook an investigation to define active areas of cellular proliferation and programmed cell death spatially and temporally during development of human fetal external ...
Baskin, Laurence, Cao, Mei, Cunha, Gerald R, Isaacson, Dylan, Li, Yi, Overland, Maya, Sinclair, Adriane   +6 more
core  

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Inhibidores de la Caspasa 8 [PDF]

, 2018
Esta revisión bibliográfica trata de explicar de forma sencilla qué son los inhibidores de la caspasa 8. Para ello se explicará en principio qué es la muerte celular, qué tipos de muerte celular se llevan a cabo en la célula, la vía de muerte celular ...
Ocaña Campos, Rocío
core  

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source

MPI‐Guided Photothermal Therapy of Prostate Cancer Using Stem Cell Delivery of Magnetotheranostic Nanoflowers

Advanced Functional Materials, EarlyView.
Tumor‐tropic human mesenchymal stem cells (hMSCs) were used as delivery vehicles for magnetotheranostic gold–iron oxide nanoflowers. Magnetic particle imaging of the iron component demonstrated widespread intratumoral distribution and sustained retention in contrast to injection of naked nanoflowers.
Behnaz Ghaemi, Ana Rosu, Shreyas Kuddannaya, Gautier Laurent, Rana Bazzi, Stéphane Roux, Ali Shakeri‐Zadeh, Jeff W. M. Bulte   +7 more
wiley   +1 more source

Long Noncoding RNA H19/miR-675 Axis Promotes Gastric Cancer via FADD/Caspase 8/Caspase 3 Signaling Pathway

Cellular Physiology and Biochemistry, 2017
Background: Long noncoding RNA (lncRNA) H19 is emerging as a vital regulatory molecule in the progression of different types of cancer and miR-675 is reported to be embedded in H19's first exon.
Jin Yan, Yifeng Zhang, Qiang She, Xuan Li, Lei Peng, Xiaoyong Wang, Shiyu Liu, Xiaoran Shen, Weifeng Zhang, Yu Dong, Jieyu Lu, Guoxin Zhang   +11 more
doaj   +1 more source

PENGARUH TERAPI N-ASETIL SISTEIN TERHADAP KADAR HIGH MOBILITY GROUP BOX-1 DAN EKSPRESI CASPASE-3 PADA MENCIT INDUKSI SIKLOSPORIN [PDF]

, 2016
Nugraheni Irda. S501102045. 2016. Pengaruh Terapi N-Asetil Sistein Terhadap Ekspresi High Mobility group Box-1 dan Caspase-3 pada Mencit Induksi Siklosporin. TESIS. Pembimbing I : Prof. Dr. dr. H. M Bambang Purwanto, Sp.PD-KGH, FINASIM, Pembimbing II: Dr.
Irda, Nugraheni
core   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Protective and therapeutic effects of cannabis plant extract on liver cancer induced by dimethylnitrosamine in mice

Alexandria Journal of Medicine, 2014
Hepatocellular carcinomas will emerge as a major form of malignancy in the coming decades. When these tumors are in advanced stages, few therapeutic options are available.
Neveen Abd El Moneim Hussein, Mervat Abd El-Fattah El-Toukhy, Amany Hussein Kazem, Mahmoud El-Said Ali, Mohammad Abd El-Rahman Ahmad, Hossam Mahmoud Rashad Ghazy, Ahmed Mohamed Gamal El-Din   +6 more
doaj   +1 more source

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Advanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi, Nadia Vertti‐Quintero, Julien Husson, Anne‐Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud   +7 more
wiley   +1 more source