Results 281 to 290 of about 29,420 (294)
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Caspofungin for treatment of invasive aspergillus infections
Mycoses, 2008SummaryInvasive aspergillosis showed an increasing incidence during the last decades. Especially for immune‐suppressed haematological patients as well as for solid organ transplant recipients, this infection remains a life‐threatening complication.
Werner J. Heinz, H. Einsele
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SAFETY EXPERIENCE WITH CASPOFUNGIN IN PEDIATRIC PATIENTS
Pediatric Infectious Disease Journal, 2009We analyzed the caspofungin safety experience in 5 clinical registration studies in 171 pediatric patients, 1 week to 17 years of age. Caspofungin was administered for 1 to 87 (mean 12.1) days. The most common drug-related adverse events were fever, increased AST, increased ALT, and rash; few events were serious or required treatment discontinuation ...
Thomas Lehrnbecher +13 more
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Journal of Antimicrobial Chemotherapy, 2019
BACKGROUND Candida auris is an emerging MDR pathogen. It shows reduced susceptibility to azole drugs and, in some strains, high amphotericin B MICs have been described. For these reasons, echinocandins were proposed as first-line treatment for C.
Catiana Dudiuk +10 more
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BACKGROUND Candida auris is an emerging MDR pathogen. It shows reduced susceptibility to azole drugs and, in some strains, high amphotericin B MICs have been described. For these reasons, echinocandins were proposed as first-line treatment for C.
Catiana Dudiuk +10 more
semanticscholar +1 more source
Caspofungin in a pediatric patient with persistent candidemia
Pediatric Critical Care Medicine, 2004To describe the response of a child with persistent fungemia to caspofungin, a member of the echinocandin class of antifungals.Descriptive case report.Pediatric intensive care unit at a university teaching hospital.A 3-yr-old female with persistent candidemia.After >5 wks of persistent candidemia, caspofungin was added to an antifungal regimen that ...
Karin K. Wertz, Robert K. Pretzlaff
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Caspofungin Therapy of Neonates With Invasive Candidiasis
Pediatric Infectious Disease Journal, 2004Invasive candidiasis is an increasing problem in neonatal intensive care units worldwide and is an important cause of morbidity, mortality and prolongation of hospital stay. Despite administration of amphotericin B, invasive candidiasis in neonates is sometimes complicated by persistent fungemia and refractory invasive candidiasis. The problem has been
Carlos E Castro +8 more
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Future Microbiology
Antifungal infections are becoming a major concern to human health due to antimicrobial resistance. Echinocandins have been promising agents against resistant fungal infections, primarily caspofungin, which has a more effective mechanism of action than azoles and polyenes.
Tawanny KB Aguiar +7 more
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Antifungal infections are becoming a major concern to human health due to antimicrobial resistance. Echinocandins have been promising agents against resistant fungal infections, primarily caspofungin, which has a more effective mechanism of action than azoles and polyenes.
Tawanny KB Aguiar +7 more
openaire +2 more sources
Journal of Antimicrobial Chemotherapy, 2019
OBJECTIVES Investigate the efficacy of caspofungin in participants
Jason Y Kim +6 more
semanticscholar +1 more source
OBJECTIVES Investigate the efficacy of caspofungin in participants
Jason Y Kim +6 more
semanticscholar +1 more source
The use of caspofungin in HIV-infected individuals
Expert Opinion on Investigational Drugs, 2007Fungal infections are a significant cause of HIV-related morbidity and mortality, particularly in the developing world, but also in countries with access to highly active antiretroviral therapy. New agents are essential to improve present efficacy rates, particularly in cases of drug resistance.
Mark Nelson, Laura Waters
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