Results 61 to 70 of about 791,472 (342)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Effects of defects on laminate quality and mechanical performance in thermoplastic Automated Fiber Placement-based process chains

open access: yesAdvanced Manufacturing: Polymer & Composites Science, 2019
Automated Fiber Placement of thermoplastic unidirectional tape materials offers several advantages over conventional organosheets, such as enhanced part performance through tailored fiber architecture, and economic and ecological benefits due to scrap ...
Thomas Zenker   +2 more
doaj   +1 more source

Proses performance monitoring in pewter manufacturing [PDF]

open access: yes, 1998
This paper reports a study on the casting parameters of pewter based on the Taguchi approach. The quality attributes investigated are shrinkage, hardness and microstructure.
Musa, Hamidon, Thean, Chan Tan
core  

Treating lupus nephritis patients to lupus low disease activity reduces renal relapse and preserves long‐term kidney function

open access: yesArthritis Care &Research, Accepted Article.
Objective Lupus low disease activity state (LLDAS) is a validated treatment target in systemic lupus erythematosus (SLE) but limited studies have explored the role of LLDAS in lupus nephritis (LN). This study aims to investigate the frequency and predictors of LLDAS attainment, and its benefit on LN relapse and renal function preservation in patients ...
Chak Kwan Cheung   +6 more
wiley   +1 more source

Numerical simulation of mold filling and casting solidification [PDF]

open access: yes, 2008
Cílem této diplomové práce je, na základě numerické simulace stávající technologie výroby hliníkového odlitku držáku kladky V9X, analyzovat příčiny vzniku vad typu zavaleniny a studené spoje.
Kolda, Vlastimil
core  

CDDT: Fast Approximate 2D Ray Casting for Accelerated Localization

open access: yes, 2018
Localization is an essential component for autonomous robots. A well-established localization approach combines ray casting with a particle filter, leading to a computationally expensive algorithm that is difficult to run on resource-constrained mobile ...
Karaman, Sertac, Walsh, Corey
core   +1 more source

Identifying High‐Impact Solutions to Address Racial and Ethnic Health Disparities in Lupus: A Consensus‐Based Approach

open access: yesArthritis Care &Research, Accepted Article.
Objective We conducted formative research aimed at identifying solutions that address inequitable health outcomes in lupus due to adverse social determinants of health. Methods We conducted a search for keywords which provided insights into potential solutions and initiatives underway. An advisory panel of lupus experts iteratively reviewed the list of
Joy Buie   +11 more
wiley   +1 more source

IMPROVEMENT OF THE SMELTING TECHNOLOGY OF STEEL IN ACIDIC AND BASIC ELECTRIC ARC FURNACES IN «SAMARA PLANT TECHNICAL CASTING» WITH THE USE OF DISPERSED MATERIALS

open access: yesЛитьë и металлургия, 2013
Efficiency of using particulate materials as deoxidazing mixtures for steel diffusive deoxidation in acid and basic furnaces is shown.
A. V. Chaikin   +3 more
doaj  

Correlation between current and cross-sectional area of parallel fixed-movable dual electrodes in ESC

open access: yesChina Foundry, 2020
Electroslag casting with parallel fixed-movable dual electrodes is a new method for achieving better quality of castings in complex mold cavities. In this work, a mathematical model, y=kx2+(k+1)x, was established to describe the ideal correlation between
Li-ting Zhao, Yun-long Xiong, Rui Chen
doaj   +1 more source

Examination of anticipated chemical shift and shape distortion effect on materials commonly used in prosthetic socket fabrication when measured using MRI: a validation study [PDF]

open access: yes, 2013
The quality of lower-limb prosthetic socket fit is influenced by shape and volume consistency during the residual limb shape-capturing process (i.e., casting). Casting can be quantified with magnetic resonance imaging (MRI) technology.
Buis, Adrianus   +2 more
core   +1 more source

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