Results 31 to 40 of about 2,889 (110)

The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo, Li Li, Fang Wang, Wen Liu, Yan Zhang   +4 more
wiley   +1 more source

A Case of Retroperitoneal Castleman’s Disease and an Update on the Latest Evidence

Case Reports in Surgery, 2014
Castleman’s disease is a benign lymphoproliferative condition with three distinct histological subtypes. Clinically it presents in either a unicentric or multicentric manner and can affect various anatomic regions, the mediastinum being the most frequent
Eleftherios Spartalis, Petros Charalampoudis, Apostolos Kandilis, Antonios Athanasiou, Petros Tsaparas, Athanasios Voutsarakis, Ioannis D. Kostakis, Dimitrios Dimitroulis, Evanthia Svolou, Penelope Korkolopoulou, Nikolaos Nikiteas, Gregory Kouraklis   +11 more
doaj   +1 more source

Idiopathic Multicentric Castleman Disease Associated With Seronegative Erosive Chronic Polyarthritis: A Diagnostic Challenge

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Idiopathic multicentric Castleman disease can rarely present with systemic inflammation and erosive seronegative polyarthritis. Awareness of this association helps prevent misdiagnosis and ensures appropriate immunosuppressive management based on clinicopathological and immunohistochemical correlation.
Birahim Lo, Baïdy Sy Kane, Fatine Benjelloun, Mouhamed Almakhy Niang, Ibra Kaïré, Charifah Siddiki, Avotra Razafimandimby, Hamidou Deme, Cherif Mouhamed Moustapha Dial, Abdoulaye Pouye   +9 more
wiley   +1 more source

Laparoscopic treatment of abdominal unicentric castleman’s disease: a case report and literature review

BMC Surgery, 2017
Background Castleman’s disease is a rare lymphoproliferative disorder of unknown etiology that most commonly presents as a mediastinal nodal mass. It is exceptionally uncommon for Castleman’s disease to present in the mesentery and, only 53 cases have ...
Umberto Bracale, Francesco Pacelli, Marco Milone, Umberto Marcello Bracale, Maurizio Sodo, Giovanni Merola, Teresa Troiani, Enrico Di Salvo   +7 more
doaj   +1 more source

Diagnostic Yield of EBUS Mediastinal Cryobiopsy Versus TBNA in Suspected Lymphoproliferative Disorders: A Prospective Multicentre Study

Respirology, Volume 31, Issue 9, Page 903-911, September 2026.
We assessed the diagnostic yield of EBUS‐guided transbronchial mediastinal cryobiopsy (EBUS‐TBMC) compared with EBUS‐transbronchial needle aspiration (EBUS‐TBNA) in patients with suspected mediastinal lymphoproliferative disorders (LPDs). EBUS‐TBMC was superior to EBUS‐TBNA and achieved a high diagnostic yield in patients with suspected mediastinal ...
Yaniv Dotan, Ayal Romem, Elad Guber, Michael Kassirer, Daphne Felus, Nimrod Urtreger, Ophir Freund, Hanna A. Dawood, Boaz Tiran, Doron Cohn‐Schwartz, Sarah Borsekofsky, Amir Bar‐Shai, Evgeni Gershman   +12 more
wiley   +1 more source

Systemic connective tissue disease complicated by Castleman's disease: report of a case and review of the literature

Haematologica, 2004
Castleman's disease is an atypical lymphoproliferative disorder characterized by the prevalence of B CD5-positive cells in the marginal zone. Autoimmune manifestations have often been reported, but the association of Castleman's disease with systemic ...
G De Marchi, S De Vita, M Fabris, CA Scott, G Ferraccioli   +4 more
doaj  

Surgical management of abdominal and retroperitoneal Castleman's disease

World Journal of Surgical Oncology, 2005
Background Abdominal and retroperitoneal Castleman's disease could present either as a localized disease or as a systemic disease. Castleman's disease is a lymphoid hyperplasia related to human Herpes virus type 8, which could have an aggressive behavior,
Huber Olivier, Ris Frederic, Zufferey Guillaume, Chassot Gilles, Bucher Pascal, Morel Philippe   +5 more
doaj   +1 more source

Transitional type of Castleman's disease manifested as the POEMS syndrome [PDF]

Vojnosanitetski Pregled, 2004
Background. Castleman’s disease is an atypical lymphoproliferative disorder characterized by angiofollicular hyperplasia of lymph nodes. Histologically it can be classified into a hyaline-vascular type, plasma-cell type, and transitional (mixed-cell ...
Tomić Ilija, Plavec Goran, Tasić Olga, Ristanović Aleksandar, Cvijanović Vlado   +4 more
doaj   +1 more source

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta, Ashish Sharma, Bernd Meibohm   +2 more
wiley   +1 more source

Castleman’s disease of the neck: report of a case and review of the literature

B-ENT, 2009
Castleman’s disease of the neck: report of a case and review of the literature. Objectives: Castleman’s disease is an uncommon disease of benign lymph node hyperplasia primarily affecting the mediastinum, with the head and neck region being the second ...
K. D. Markou, J. K. Goudakos, G. Psillas, A. Antoniadis, I. Karasmanis, V. Vital, A. Nicolaou   +6 more
doaj   +2 more sources