Results 131 to 140 of about 650,104 (308)

Cabazitaxel: a novel second-line treatment for metastatic castration-resistant prostate cancer

, 2011
Channing J Paller, Emmanuel S AntonarakisSidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD, USAAbstract: Until recently, patients with castration-resistant prostate cancer (CRPC) had limited therapeutic options once they became ...
Channing J Paller, Emmanuel S Antonarakis   +1 more
core  

Management of Advanced Prostate Cancer in the Asia‐Pacific Region: Summary of the Asia‐Pacific Advanced Prostate Cancer Symposium 2025

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Summary of the Asia Pacific Advanced Prostate Cancer Symposium 2025, showing disciplines and diversity of participants, discussion topics (high‐risk localized/locally advanced prostate cancer; PSA persistence and recurrence; radioligand therapy; genetics and genomics; bone protection and other aspects of supportive care), key themes, and high‐level ...
Edmund Chiong, Renu Eapen, Nicholas Buchan, Kenneth Chen, Lukman Hakim, Agus Rizal Hamid, Jae‐Young Joung, Ravindran Kanesvaran, Makarand Khochikar, Jason Letran, Bannakij Lojanapiwat, Indranil Mallick, Chi Fai Ng, Pei Ing Ngam, Teng Aik Ong, Jacob Pang, Darren M. C. Poon, Natasha Roberts, Marniza Saad, Shinichi Sakamoto, Jeremy Tey, Sue Ping Thang, Poh Choo Toh, Levent Türkeri, Nguyễn Tuấn Vinh, Alvin Wong, Yao Zhu, ANZUP Cancer Trials Group, Ian D. Davis   +28 more
wiley   +1 more source

PROCA11 early activation fuels prostate cancer neuroendocrine traits by regulating cell survival and migration

iScience
Summary: Tumor plasticity drives the emergence of castration-resistant and neuroendocrine prostate cancer following androgen-deprivation therapy (ADT).
Rocco Cipolla, Marc Gabriel, Ugo Szachnowski, Zhimin Wang, Martina Romani, Giorgia Ianese Regin, Micaela Piemontese, Virginie Firlej, Marina Pinskaya, Antonin Morillon   +9 more
doaj   +1 more source

Integrin α6 Activity in Castration-Resistant Prostate Cancer

, 2017
Although castration-resistant prostate cancers no longer respond to anti-androgen therapies, the androgen receptor (AR) is still required to promote tumor survival.
Nollet, Eric A.
core  

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

Andrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Caveolin-1 and -2 regulate cell motility in castration-resistant prostate cancer

, 2018
Toyoharu Kamibeppu, Koji Yamasaki, Kozue Nakahara, Takahiro Nagai, Naoki Terada, Hiromasa Tsukino, Shoichiro Mukai, Toshiyuki Kamoto Department of Urology, Faculty of Medicine, University of Miyazaki, Kiyotake, Japan Background: Caveolin (Cav)-1 and Cav ...
Nakahara K, Kamoto T, Nagai T, Mukai S, Kamibeppu T, Yamasaki K, Tsukino H, Terada N   +7 more
core  

Melioidosis in companion animals: Analysis of 45 Australian cases (24 dogs; 21 cats) from 1997 to 2025 and a brief review of the animal and human literature

Australian Veterinary Journal, EarlyView.
Objective To report 45 cases of melioidosis in dogs and cats from northern Australia and analyse trends in epidemiology, clinical presentation, pathogenesis and response to treatment over a 27‐year period. Design Retrospective and prospective analysis of clinical records.
K Lee, C Shilton, S Benedict, M Krockenberger, M Mayo, BJ Currie, R Malik   +6 more
wiley   +1 more source

Intraindividual epigenetic heterogeneity underlying phenotypic subtypes of advanced prostate cancer

Nature Communications
Castration-resistant prostate cancer is a heterogeneous disease with variable phenotypes commonly observed in later stages of the disease. These include cases that retain expression of luminal markers and those that lose hormone dependence and acquire ...
Kei Mizuno, Sheng-Yu Ku, Varadha Balaji Venkadakrishnan, Martin K. Bakht, Michael Sigouros, Joanna Chan, Anna Trigos, Jordan H. Driskill, Jyothi Manohar, Abigail King, Adam G. Presser, Min Jin Kim, Alok K. Tewari, Henry W. Long, David Quigley, Toni K. Choueiri, Steven Balk, Sarah Hill, Juan Miguel Mosquera, David Einstein, Shahneen Sandhu, Mary-Ellen Taplin, Himisha Beltran   +22 more
doaj   +1 more source

Nuclear receptor profiling in prostatospheroids and castration-resistant prostate cancer

, 2018
Nuclear receptors (NRs), which belong to a superfamily of transcription factors and consist of a total of 48 members in humans, govern the expression of genes involved in a board range of developmental, reproductive, metabolic and immunological programs.
Jeremy Yuen-Chun Teoh, Yuliang Wang, Franky L Chan, Chi-Fai Ng, Zhu Wang, Dinglan Wu, Shan Yu   +6 more
core   +1 more source

Active surveillance for intermediate risk prostate cancer: the Manitoba Prostate Center experience

BJU International, EarlyView.
Objectives To report long‐term oncological outcomes of men with intermediate‐risk prostate cancer managed with active surveillance at a single centre. Subjects/Patients and Methods We retrospectively analysed a prospectively maintained Manitoba Prostate Centre active surveillance database.
Steven Lu, Connor Roque, Jeff Saranchuk, Ardalan E. Ahmad   +3 more
wiley   +1 more source