Results 181 to 190 of about 67,507 (290)

The Histone Methyltransferase KMT2D Is a Critical Mediator of Lineage Plasticity and Therapeutic Response in Castration-Resistant Prostate Cancer. [PDF]

Cancer Res
Kittane S, Ladewig E, Li T, Love JR, Blawski R, Gao Y, Arruabarrena-Aristorena A, Zhao P, Dalrymple SL, Liu H, Guo X, Sallaku M, Kelkar N, Garcia-Martinez L, Carmona Sanz J, Chen W, Stoudmann C, Baldino L, Razavi-Mohseni M, Kalemi I, Beer MA, Castel P, Brennen WN, Scaltriti M, Morey L, Cocco E, Ji H, Chan HM, Battle A, Leslie CS, Karthaus WR, Toska E.   +31 more
europepmc   +1 more source

Single‐Cell Morphomechanics of Prostate Cancer‐Associated Fibroblasts Identifies Distinct Features Associated with Patient Outcome

Advanced Science, Volume 13, Issue 13, 3 March 2026.
Cancer‐associated fibroblasts (CAFs) in prostate tumors exhibit distinct morphomechanical traits vs normal fibroblasts, including greater stiffness and volume, more elongated stress fibres, and larger and more elongated nuclei. These features, quantified through imaging and real‐time deformability cytometry, correlate with patient outcomes and can be ...
Antje Garside, Angela Jacobi, Shivakumar Keerthikumar, Vaibhav Mahajan, Michelle Richards, Birunthi Niranjan, Linda Teng, Nicholas Choo, Johannes Low Jun Wei, Gail P Risbridger, Mitchell G Lawrence, Anna V. Taubenberger   +11 more
wiley   +1 more source

Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Neuromodulatory subcortical systems (NSSs) are uniquely susceptible to dementia‐related pathology, leading to frequent molecular and behavioral impairments associated with altered function of these nuclei. Some of these systems display clear sex‐specific cytoarchitecture and signaling leading to distinct physiology and behavioral outputs in ...
Rosaria J. Rae, Jessica Marie Hunter Alberhasky, Marion Baillet, Debra A. Bangasser, Michael E. Belloy, Anne S. Berry, Chiara Berteotti, Hannah Bow, Rachel Buckley, Jessica Z. K. Caldwell, Matteo Carpi, Benjamin J. Clark, Claire J. Ciampa, Alexander C. Conley, Martin J. Dahl, Zoe R. Donaldson, Alexander J. Ehrenberg, Gillian Einstein, Neus Falgàs, Haley A. Fenlon, Megan C. Fitzhugh, Robert C. Froemke, Clara Gallay, Lea Tenenholz Grinberg, Derek A. Hamilton, Zia Hasan, Oihane Uriarte Huarte, Shaista Jabeen, Heidi I. L. Jacobs, Louis John Kolling, Elouise A. Koops, Sabrina Lenzoni, Claudio Liguori, Riccardo Manca, Catherine A. Marcinkiewcz, Tamunotonye Omoluabi, Rademene Oria, Caitlin A. Orsini, Nancy Elizabeth Ortega, Judy Pa, Nathan S. Pentkowski, Joana B. Pereira, Rhudovic Ramos, Derya Sargin, Abhijit Satpati, Maria Clara Selles, Mabel Seto, Shabana M. Shaik, Shireen Sindi, Gowoon Son, Valentine Ucheagwu, Maxime Van Egroo, Qi Yuan, Michael A. Kelberman   +53 more
wiley   +1 more source

Androgenic effects of 11-oxyandrogens in castration-resistant prostate cancer. [PDF]

BMC Cancer
Lapointe-Belleau A, Rouleau M, Villeneuve L, Descarreaux J, Caron P, Beaudoin C, Uchil A, Simonyan D, Dahmani C, Joly-Beauparlant C, Gélinas V, Droit A, Marcoux N, Castonguay V, Lacombe L, Lévesque É, Guillemette C.   +16 more
europepmc   +1 more source

Interrogating the Rhodes Must Fall Student Protests Through Fanonian Sociogeny: A Psychosocial Analysis of Historical Trauma and Political Violence in Postapartheid South Africa

International Journal of Applied Psychoanalytic Studies, Volume 23, Issue 1, March 2026.
ABSTRACT This article employs Frantz Fanon's sociogenic method to analyze the MustFall# student protest movement as an illustration of the psychic afterlife of colonialism in postapartheid South Africa. Fanon's sociogeny, which locates the formation of subjectivity in the reciprocal interplay between the psychic and the political, offers a framework ...
Veeran Naicker
wiley   +1 more source

Disintegration, Salvation, and/or Madness in Dostoevsky

International Journal of Applied Psychoanalytic Studies, Volume 23, Issue 1, March 2026.
ABSTRACT Psychological fragmentation and derangement suffuse Dostoevsky's fiction. This paper argues that the madness of Dostoevsky characters derives from intense wounds to the self: humiliating lacerations that impel fugue and disintegration. Such vulnerable, frangible characters seek to escape and deny themselves to avoid being seen for who they are.
Jerry Piven
wiley   +1 more source

Two Cases of Metastatic Castration-Resistant Prostate Cancer With Long-Term Survival Treated With Abiraterone. [PDF]

Clin Case Rep
Une M, Yamamoto S, Fuse H, Fujiwara R, Yonese J, Noda K.   +5 more
europepmc   +1 more source

Cytoreductive Radical Prostatectomy in Oligometastatic Prostate Cancer: Single‐Centre Experience

BJUI Compass, Volume 7, Issue 3, March 2026.
Abstract Objective This study aims to evaluate the oncological outcomes, functional recovery and overall satisfaction following cytoreductive radical prostatectomy (CRP) in patients with oligometastatic prostate cancer treated at a single tertiary‐care centre.
Khawaja Abdul Rouf, Akil Latief, Sajad Ahmad Para, Younis Mushtaq, Shubham Gupta, Sajad Ahmad Malik, Saqib Mehdi, Arif Hamid   +7 more
wiley   +1 more source

Rethinking combination strategies in metastatic castration-resistant prostate cancer (mCRPC)-lessons from KEYNOTE-641. [PDF]

Transl Androl Urol
Nguyen MD, Vinh-Hung V, Verschraegen C, Wang P.   +3 more
europepmc   +1 more source

Extended versus limited pelvic lymph node dissection and long‐term outcomes in high‐risk prostate cancer before radiotherapy

BJUI Compass, Volume 7, Issue 3, March 2026.
Abstract Objectives To compare oncological outcomes after extended pelvic lymph node dissection (PLND) versus limited in patients with high‐risk prostate cancer (PCa) undergoing curative external beam radiation therapy (EBRT). Patients and Methods From 3627 men with PCa at a single centre between 2000 and 2013, 167 with high‐risk, age ≤75, Gleason ...
Georgios Daouacher, Jessica Carlsson, Pernilla Sundqvist, Mauritz Waldén   +3 more
wiley   +1 more source