Results 31 to 40 of about 3,811,568 (245)
20(S)-protopanaxadiol inhibition of progression and growth of castration-resistant prostate cancer. [PDF]
PLoS ONE, 2014 Castration-resistant progression of prostate cancer after androgen deprivation therapies remains the most critical challenge in the clinical management of prostate cancer.Bo Cao, Yanfeng Qi, Yan Yang, Xichun Liu, Duo Xu, Wei Guo, Yang Zhan, Zhenggang Xiong, Allen Zhang, Alun R Wang, Xueqi Fu, Haitao Zhang, Lijing Zhao, Jingkai Gu, Yan Dong +14 moredoaj +1 more sourceIdentification of kinases regulating prostate cancer cell growth using an RNAi phenotypic screen. [PDF]
PLoS ONE, 2012 As prostate cancer progresses to castration-resistant disease, there is an increase in signal transduction activity. Most castration-resistant prostate tumors continue to express the androgen receptor (AR) as well as androgen-responsive genes, despite ...Hilary Whitworth, Shriti Bhadel, Melissa Ivey, Mark Conaway, Andrea Spencer, Ronald Hernan, Heather Holemon, Daniel Gioeli +7 moredoaj +1 more sourceAutocrine activation of MAPK signaling mediates intrinsic tolerance to androgen deprivation in LY6D prostate cancer cells
Cell Reports, 2023 Summary: The emergence of castration-resistant prostate cancer remains an area of unmet clinical need. We recently identified a subpopulation of normal prostate progenitor cells, characterized by an intrinsic resistance to androgen deprivation and ...Ivana Steiner, Teresita del N.J. Flores-Tellez, Renaud Mevel, Amin Ali, Pengbo Wang, Pieta Schofield, Caron Behan, Nicholas Forsythe, Garry Ashton, Catherine Taylor, Ian G. Mills, Pedro Oliveira, Simon S. McDade, Dietmar M. Zaiss, Ananya Choudhury, Georges Lacaud, Esther Baena +16 moredoaj +1 more sourceSingle-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer
Cell Reports, 2018 Summary: The exact identity of castrate-resistant (CR) cells and their relation to CR prostate cancer (CRPC) is unresolved. We use single-cell gene profiling to analyze the molecular heterogeneity in basal and luminal compartments.João D. Barros-Silva, Douglas E. Linn, Ivana Steiner, Guoji Guo, Adnan Ali, Hubert Pakula, Garry Ashton, Isabel Peset, Michael Brown, Noel W. Clarke, Roderick T. Bronson, Guo-Cheng Yuan, Stuart H. Orkin, Zhe Li, Esther Baena +14 moredoaj +1 more sourceManagement of patients with advanced prostate cancer—metastatic and/or castration-resistant prostate cancer: report of the Advanced Prostate Cancer Consensus Conference (APCCC) 2022 [PDF]
, 2023 Background:
Innovations in imaging and molecular characterisation together with novel treatment options have improved outcomes in advanced prostate cancer. However, we still lack high-level evidence in many areas relevant to making management decisions Yu, EY, Matthew Smith, Jereczek-Fossa, Barbara A., Efstathiou, J, Briganti, Alberto, Merseburger, Axel Stuart Stuart, Yu, Evan Y., Ekeke, O.N., Efstathiou, E, Jereczek-Fossa, Barbara Alicja, Bristow, R.G., Kramer, G., Higano, Celestia S., Higano, C, Dana Rathkopf, Christopher Logothetis, Heinrich, Daniel, Nicholas D. James, Poon, Darren M. C., Ryan, Charles J, Rabah, Danny M, Hussain, M., Sandy Srinivas, Herrmann, K, Pritchard, Colin C., Kramer, G, Morgans, AK, Sartor, O, Davis, I.D., Sade, J.P., Eric Small, Vapiwala, N, Onyeanunam Ngozi Ekeke, Briganti, A., Sade, JP, Valerie Fonteyne, Nguyen, PL, Fizazi, Karim S., Colin C. Pritchard, Clarke, Caroline S., Kramer, Gero, Logothetis, C, Evans, CP, Steuber, T, Sternberg, Cora N., Aparicio, Ana M., Davis, ID, Walz, J., Evan Y. Yu, Hofman, M.S., Murphy, Declan G, Spratt, DE, Efstathiou, J., Rob Jones, Clarke, Noel W., Sharifi, N., Srinivas, S., Beer, T.M., Attard, G, Daugaard, G, Oh, WK, Sharifi, Nima, Inge van Oort, Morgans, Alicia K, Mehra, N, Gillessen, S., Leibowitz, Raya, Padhani, Anwar R, Muhammad Bulbul, Celestia Higano, Davis, Ian D, Dan George, van Oort, I, Hirotsugu Uemura, Jereczek-Fossa, B.A., Bulbul, M., Christopher P. Evans, Mark A. Rubin, Bristow, Rob G, Poon, Ming Chun Darren, Kanesvaran, R, Mahal, B, Kim N. Chi, Maria De Santis, Castro, E., Ost, P., Raja Leibowitz, Mahal, B., Hiroji Uemura, Mottet, N, Efstathiou, Jason, Khauli, R.B., Davis, Ian D., Raja B. Khauli, Elena Castro, Beltran, H, Armstrong, A.J., Horvath, Lisa G., Ana M. Aparicio, Hofman, Michael S, Chi, Kim N., Gedske Daugaard, Gillessen, S, Alicia K. Morgans, Matthew R. Sydes, Rabah, D.M., de Bono, Johann Sebastian, Antonarakis, E.S., Maluf, Fernando Cotait, Saad, Fred, Zapatero, Almudena, Halabi, S., Pezaro, CJ, Susan Halabi, George, D., Mahal, Brandon A., Cora N. Sternberg, O'Sullivan, Joe M; id_orcid, Walz, Jochen, Mukherji, Deborah, Joe M. O’Sullivan, Jones, Robert, Small, E, James, Nicholas D., Omlin, A., Sweeney, Christopher J., Fanti, Stefano, Sharifi, N, Clarke, C.S., Piet Ost, Vedang Murthy, Fossati, Nicola, Bristow, Robert G., Eeles, R., Daniel Castellano, Daniel Heinrich, Declan G. Murphy, Nicolas Mottet, Claire L. Vale, Jones, Rob, Leibowitz, R., Soule, Howard R., Yamoah, K., Eeles, Ros A., Matheson, David, Pierre Blanchard, Carmel J. Pezaro, Feng, Felix Y, Neal Shore, Steuber, T., Merseburger, A., Soule, Howard, Jones, Robert J., Chowdhury, S., van Oort, I., Ürün, Yüksel, van Oort, Inge M., Tombal, B., James, N.D., Vale, Claire L., Small, E., Nguyen, Paul L., Cheng, Heather H., Alberto Briganti, Soule, H, Castellano, D., Higano, Celestia, Maluf, F., O’Sullivan, J.M., De Santis, M, Bossi, Alberto, Beer, Tomasz M., Armstrong, Andrew J., Uemura, H., Frydenberg, Mark, Uemura, Hirotsugu, Silke Gillessen, Taplin, M-E, Tilki, D., Castellano, D, Saad, F, Evans, Christopher P., Aparicio, AM, Efstathiou, Jason Alexander, Mukherji, D., Suzuki, H., Sweeney, Christopher J, Clarke, Noel, Padhani, Anwar R., Emmanuel S. Antonarakis, de Bono, Johann, Skoneczna, Iwona, Ye, Dingwei, Hind Mrabti, O'Sullivan, Joe M, Armstrong, Andrew J, Yamoah, Kosj, Logothetis, Christopher J, Tilki, Derya, Ost, P, Ryan, CJ, Merseburger, Axel, Kellokumpu-Lehtinen, Pirkko-Liisa, Gerhardt Attard, Kellokumpu-Lehtinen, P.L., Caroline S. Clarke, Gravis, G., Gillessen, Silke, Spratt, Daniel E, Jones, R., Ignacio Duran, Skoneczna, I, Mateo, J., Eleni Efstathiou, Castellano, Daniel, Almudena Zapatero, Spratt, D.E., Walz, Jochen Christoph, Eeles, R, Logothetis, Christopher J., Bulbul, M, Logothetis, Christopher, Michael S. Hofman, Turco, F, Cheng, Heather H, Gravis, Gwenaelle, Scher, Howard I, Bristow, RG, Mottet, N., Jason Efstathiou, Johann de Bono, Frydenberg, M., Vapiwala, N., Barbara A. Jereczek-Fossa, Spratt, Daniel E., Eeles, Ross, Sternberg, CN, Alberto Bossi, Pritchard, Colin C, Gwenaelle Gravis, Fernando Maluf, Thomas Steuber, Srinivas, S, Vale, C.L., Bjartell, Anders S., Mary-Ellen Taplin, Shore, Neal, Bjartell, Anders, Darren M.C. Poon, Briganti, A, Castro, Elena, Rubin, Mark A., Niven Mehra, Halabi, Susan, Gleave, M, Leibowitz, Raja, Horvath, Lisa G, Antonarakis, ES, Bertrand Tombal, Bulbul, Muhammad, James, Nicholas D, Fonteyne, V, Yu, E.Y., Christopher J. Sweeney, Smith, Matthew, Nima Sharifi, Mrabti, H., Maluf, Fernando, Ürün, Y, Kellokumpu-Lehtinen, Pirkko Liisa Irmeli, Ross Eeles, Hussain, Maha H.A., Karim Fizazi, James, ND, Small, Eric, Walz, J, Fonteyne, Valerie, Zilli, T., Fabio Turco, Klotz, Laurence, Hussain, Maha, Aparicio, A.M., Chi, Kim N, Tomasz M. Beer, Poon, Darren M C, Rubin, M.A., David Matheson, de Bono, J, Kellokumpu-Lehtinen, PL, Türkeri, Levent N., Taplin, Mary-Ellen, Türkeri, L, Duran, I, Rathkopf, D, Uemura, H, Ekeke, Onyeanunam, Herrmann, Ken, Daugaard, G., Oh, W.K., Hussain, M, Jereczek-Fossa, BA, George, Daniel J., Eeles, Ros, Beltran, Himisha, Ian D. Davis, Simon Chowdhury, Reiter, RE, Ravindran Kanesvaran, Duran, I., Evans, C.P., Omlin, Aurelius, Zapatero, A, Padhani, A.R., Murthy, V., Feng, Felix Y., Maluf, F, Higano, C., Murthy, V, Leibowitz, R, Caffo, O., Mark Frydenberg, Smith, Matthew Raymond, Morris, MJ, Duran, Ignacio, Small, Eric Jay, Mateo, Joaquin, Fossati, N, Fizazi, Karim, Murthy, Vedang, Fonteyne, V., Nicola Fossati, Nguyen, Paul L, Aparicio, Ana M, Tombal, B, Cheng, H.H., Clarke, Caroline S, Howard I. Scher, Mrabti, H, Türkeri, Levent, Clarke, N., Caffo, O, Reiter, Robert E, Shore, N., Sydes, M.R., Turco, Fabio, Klotz, Laurence H., Martin Gleave, Yüksel Ürün, De Santis, M., Khauli, RB, Yamoah, K, Omlin, A, Kosj Yamoah, Srinivas, Sandy, Rathkopf, D., Suzuki, Hiroyoshi, Joaquin Mateo, Antonarakis, Emmanuel S, Khauli, Raja Bahjat, Matheson, D., Sydes, Matthew R, Levent Türkeri, Felix Y. Feng, Klotz, L., Ekeke, Onyeanunam Ngozi, Ost, Piet, Herrmann, K., Cheng, HH, Matheson, D, Khauli, Raja B, van Oort, Inge, Shore, N, Mateo, J, Fizazi, K, Rubin, MA, Padhani, Anwar Roshanali, Horvath, LG, Fanti, S., Kanesvaran, Ravindran, Mahal, Brandon, Thomas Zilli, Türkeri, L., Sartor, Oliver, Feng, F.Y., Vale, Claire L, George, Daniel, Neha Vapiwala, Murphy, D.G., Fanti, S, Sternberg, Cora Nanette, Attard, Gerhardt, Bulbul, Muhammad Ahmad, Beer, TM, Frydenberg, M, Jereczek-Fossa, Barbara A, Uemura, Hiroji, Omlin, Aurelius Gabriel, Bjartell, A., Vale, CL, Howard Soule, Morgans, A.K., Iwona Skoneczna, Beer, Tomasz M, Gravis, G, Turco, F., Pritchard, Colin, Padhani, AR, Fonteyne, Valérie H., Heinrich, D, Michael J. Morris, Hofman, MS, Merseburger, A, Fossati, N., Blanchard, P., Ken Herrmann, Himisha Beltran, Robert E. Reiter, Klotz, L, Mrabti, Hind, Kellokumpu-Lehtinen, P-L, Gillessen Sommer, Silke, Caffo, Orazio, de Bono, J., Daugaard, Gedske, Rabah, DM, Pezaro, Carmel J, Sweeney, Christopher, Axel Merseburger, Zilli, Thomas, Heather H. Cheng, Noel Clarke, O’Sullivan, Joe M., Vapiwala, Neha, Sternberg, Cora N, Soule, H., Ryan, Charles J., Gleave, Martin E., Blanchard, P, Antonarakis, Emmanuel S., Morris, Michael J, Scher, Howard I., Aurelius Omlin, Hiroyoshi Suzuki, Rathkopf, Dana, George, Dan, Chowdhury, Simon, Gleave, Martin, Clarke, CS, Lisa G. Horvath, Oh, William K, O'Sullivan, Joe M., Scher, HI, Pritchard, CC, Sade, Juan Pablo, Jochen Walz, Daniel E. Spratt, Pezaro, C.J., Bjartell, A, Sternberg, C.N., DMC, Poon, Morgans, Alicia K., Brandon Mahal, De Santis, Maria, Murphy, Declan G., Paul L. Nguyen, Clarke, N, Kanesvaran, R., Juan Pablo Sade, Mukherji, Deborah M., Yu, Evan Yi Wen, Rathkopf, Dana E., Tombal, Bertrand, Reiter, Robert E., Morris, Michael J., Pezaro, Carmel J., Danny M. Rabah, Evans, Christopher P, Laurence Klotz, Sartor, Oliver A., Ekeke, ON, Pritchard, C.C., Reiter, R.E., Smith, Mathew, Smith, M, Gero Kramer, Poon, DMC, Smith, M., Attard, G., Dingwei Ye, Beltran, H., Blanchard, Pierre, Efstathiou, Eleni, Scher, H.I., Anders Bjartell, Matheson, David J., Kellokumpu-Lehtinen, Pirkko Liisa, Oliver Sartor, Hofman, Michael S., Skoneczna, Iwona A., de Bono, Johann S., Tombal, B. F., James, Nicholas David, Charles J. Ryan, Jones, R, Sydes, Matthew R., Morgans, Alicia Katherine, Deborah Mukherji, Castellano, Daniel E., O'Sullivan, JM, Ye, D., Gleave, M., Morris, M.J., Shore, Neal D., Mukherji, D, Fizazi, K., Yu, Evan Y, Nguyen, P.L., Maha Hussain, Rabah, Danny M., Suzuki, H, Heinrich, D., Sweeney, C., Mottet, Nicolas, Mehra, N., Halabi, Susan S., Taplin, Mary Ellen, Pirkko-Liisa Kellokumpu-Lehtinen, Murphy, DG, Efstathiou, E., Zapatero, A., Chowdhury, S, Rob G. Bristow, Derya Tilki, Sydes, MR, Horvath, L.G., Tilki, D, Rubin, Mark A, William K. Oh, Ye, D, Skoneczna, I., Orazio Caffo, Poon, Darren M.C., Mahal, Brandon A, Armstrong, AJ, Ürün, Y., Bristow, Rob G., Feng, FY, Mehra, Niven, Logothetis, C., Anwar R. Padhani, Chi, KN, Steuber, Thomas, Stefano Fanti, Chi, K.N., Taplin, M.E., Sartor, O., Ryan, C.J., Zilli, T, Andrew J. Armstrong, Khauli, Raja B., Fred Saad, Castro, E, Halabi, S, Oh, William K., Bossi, A, Rathkopf, Dana E, Saad, F., George, D, Sweeney, CJ +568 morecore +2 more sources
