Results 171 to 180 of about 229,451 (392)

Patient‐derived xenograft models in pan‐cancer: From bench to clinic

open access: yesInterdisciplinary Medicine, EarlyView.
Abstract Patient‐derived xenograft (PDX) models provide a robust preclinical platform that preserves the genetic and phenotypic heterogeneity of patient tumors while mirroring their tumor genetic characteristics, which retain malignant cells and the tumor pathological structure, making them valuable for studying tumor progression and developing ...
Jiatong Li   +5 more
wiley   +1 more source

Self-Castration.

open access: yesJAMA: The Journal of the American Medical Association, 1901
n ...
openaire   +1 more source

A Novel In Vitro Host−Pathogen Model for Felis catus and Sporothrix Zoonotic Species Investigation

open access: yesJournal of Basic Microbiology, EarlyView.
ABSTRACT Hyperendemic zoonotic sporotrichosis, attributed to Sporothrix brasiliensis, presents a significant public health challenge in Brazil. Cats exhibit severe symptoms and high fungal loads, though their susceptibility is unclear. Sporothrix schenckii can also cause feline disease, primarily seen in Asia.
Gabriele Barros Mothé   +10 more
wiley   +1 more source

Reproductive systems of Hohenbergia Schult. & Schult.f. (Bromelioideae: Bromeliaceae) endemic to the Atlantic forest

open access: yesNordic Journal of Botany, EarlyView.
Many species of the Bromeliaceae are under threat due to the fragmentation and anthropogenic pressure affecting the Atlantic Forest highlight the need to conservation efforts. The genus Hohenbergia deserves special attention in this context, as the Hohenbergia stellata complex includes endemic species that rely on diverse reproductive strategies, which
Tiago Abreu da Silva   +7 more
wiley   +1 more source

Heterogeneous cancer-associated fibroblast population potentiates neuroendocrine differentiation and castrate resistance in a CD105-dependent manner. [PDF]

open access: yes, 2019
Heterogeneous prostatic carcinoma-associated fibroblasts (CAF) contribute to tumor progression and resistance to androgen signaling deprivation therapy (ADT).
Agarwal, Priyanka   +14 more
core   +1 more source

Preliminary genetic barcodes for ash (Fraxinus) species and generation of new wide hybrids

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Societal Impact Statement The world‐wide diversity of ash trees includes genetic information encoding resistance to the ash dieback fungus and the emerald ash borer beetle, which are currently devastating ash populations in Europe and North America. In order to mobilise this genetic diversity in conventional breeding programmes, we need to be able to ...
William J. Plumb   +11 more
wiley   +1 more source

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