Results 121 to 130 of about 52,178 (271)

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

Advanced Science, EarlyView.
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu, Min Chen, Chen‐Yu Jiang, Dai‐Ji Jiang, Xu Zhang, Xiao‐He Xu, Yi‐Wei Liu, Bei Feng, Lin‐Cai Ye, Yang‐Yang He, Xu Huang, Yi‐Chi Zhang, Xing‐Liang Zhou, Yi Shen, Tian‐Yu Liu, Li‐Jun Fu, Yi Yan, Hao Zhang   +17 more
wiley   +1 more source

Intracellular growth of Afipia felis, a putative etiologic agent of cat scratch disease [PDF]

, 1992
K A Birkness, Velma G. George, Elizabeth White, David S. Stephens, F D Quinn   +4 more
openalex   +1 more source

An Empirical Comparison of Three Inference Methods

, 2015
In this paper, an empirical evaluation of three inference methods for uncertain reasoning is presented in the context of Pathfinder, a large expert system for the diagnosis of lymph-node pathology.
Heckerman, David
core  

Tumor‐Derived Interleukin 35 Promotes Fibrosis in the Tumor Microenvironment of Pancreatic Cancer by Activating Pancreatic Stellate Cells

Advanced Science, EarlyView.
This study demonstrates that tumor‐derived IL‐35 promotes pancreatic cancer fibrosis by indirectly activating pancreatic stellate cells through IGFBP2/IGF‐1R/PI3K‐Akt and Tsp‐1/TGF‐β pathways. IL‐35 blockade reduces stromal fibrosis, restores chemosensitivity, and synergizes with gemcitabine‐based regimens, highlighting IL‐35 as a promising therapeutic
Hui Li, Huizhi Sun, Jing Liu, Yan Wu, Lin Wei, Jianming Li, Yudong Yuan, Peng Xie, Chao Xu, Guolu Luo, Yuqi Guan, Yukuan Feng, Antao Chang, Jihui Hao, Chongbiao Huang   +14 more
wiley   +1 more source

Spectrum of Optic Disc Edema with Macular Star and Neuroretinitis – A Literature Review

Delhi Journal of Ophthalmology
Neuroretinitis (NR) is a condition characterized by the fundus appearance of optic disc edema and subsequent formation of a macular star figure. What we commonly referred to as NR is now identified to be a clinical presentation in a variety of disorders ...
Snehanka Ganpat Parab, Saroj Indersain Sahdev   +1 more
doaj   +1 more source

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

Advanced Science, EarlyView.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei, Zongzheng Zhao, Ruoqi Xu, Qin Yan, Liangzi Jiang, Fuxiao Geng, Yang Gu, Tianjiao Wang, Jing Zhou, Xiao Li, Qin Yan, Chun Lu, Wan Li   +12 more
wiley   +1 more source

Detection of Bartonella henselae in domestic cats’ saliva

Iranian Journal of Microbiology, 2010
Background and Objectives: Bartonella species are being recognized as increasingly important bacterial pathogens in veterinary and human medicine. These organisms can be transmitted by an arthropod vector or alternatively by animal scratches or bites ...
K Oskouizadeh, T Zahraei-Salehi, SJ Aledavood   +2 more
doaj  

A Case of Cat Scratch Disease

, 1979
Sanetomi Eguchi, Yujiro Matsumura, Yasushi Nomura, Tomoko Yanagita, Akio Horie   +4 more
openalex   +2 more sources

Synaptic Dysfunction in the Anterior Cingulate Cortex Underlies Pain‐Anxiety Comorbidity in a Mandibular Asymmetry Mouse Model

Advanced Science, EarlyView.
This study establishes a mandibular asymmetry (MA) mouse model that recapitulates chronic orofacial pain and anxiety comorbidity. Anterior cingulate cortex (ACC) hyperactivation and synaptic dysfunction are identified as central neural mechanisms underlying these pathologies, with chemogenetic inhibition of ACC CaMKII+ neurons effectively reversing ...
Zhaoyichun Zhang, Yanran Zhang, Jialin Si, Honghui Mao, Feng He, Jin Ning, Guaiguai Ma, Xiaohua Chen, Haoxiang Xiao, Yuanyuan Zhu, Haifeng Zhang, Yifan Lu, Qian Liu, Meng Nian, Shiquan Sun, Shibin Yu, Shengxi Wu, Ze Fan, Zuolin Jin, Jing Huang   +19 more
wiley   +1 more source

Optic neuropathy secondary to cat scratch disease: case report [PDF]

, 2010
Ricardo Evangelista Marrocos de Aragão, Régia Maria Gondim Ramos, Andreya Ferreira Rodrigues Bezerra, Roberto Briand Cavalcanti Júnior, Thiago Leite Albuquerque   +4 more
openalex   +1 more source