Results 41 to 50 of about 2,312,470 (291)

Using Twitter to Infer User Satisfaction With Public Transport: The Case of Santiago, Chile

IEEE Access, 2019
User satisfaction is an important aspect to consider in any public transport system, and as such, regular and sound measurements of its levels are fundamental. However, typical evaluation schemes involve costly and time-consuming surveys.
Jose Tomas Mendez, Hans Lobel, Denis Parra, Juan Carlos Herrera   +3 more
doaj   +1 more source

Behavioral differences among domestic cats in the response to cat-attracting plants and their volatile compounds reveal a potential distinct mechanism of action for actinidine

BMC Biology, 2022
Background It has been known for centuries that cats respond euphorically to Nepeta cataria (catnip). Recently, we have shown that Lonicera tatarica (Tatarian honeysuckle), Actinidia polygama (silver vine), and Valeriana officinalis (valerian) can also ...
Sebastiaan Bol, Adrian Scaffidi, Evelien M. Bunnik, Gavin R. Flematti   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Advancing Structure-Based Drug Development: A Rebuild of the IMCA-CAT Beamline at the Advanced Photon Source [PDF]

Structural Dynamics
IMCA-CAT is a structural biology beamline located at the Advanced Photon Source (APS) that caters to pharmaceutical companies for drug discovery. During the 2023-2024 APS-U shutdown, IMCA-CAT undertook a comprehensive beamline upgrade - essentially ...
Melissa Carrillo, John P. Bacik, Erica Duguid, J. Lewis Muir, Clark Williams, Andrew Mayton, Kevin D'Amico, Stephan Ginell, Nathan Brown, Lisa J. Keefe   +9 more
doaj   +1 more source

PENGECATAN ULANG MOBIL TOYOTA CORONA TAHUN 1972 BAGIAN BELAKANG DAN ATAS [PDF]

, 2011
Proyek akhir ini berjudul Pengecatan Ulang Mobil Toyota Corona Tahun 1972 Bagian Belakang dan Atas yang bertujuan untuk: 1) Mengetahui bahan dan alat yang diperlukan untuk memperbaiki dan mengecat mobil Toyota Corona bagian belakang dan atas; 2 ...
Erwin Dwi, Prasetiya
core  

Schr\"odinger's Cat: Where Does The Entanglement Come From?

, 2017
Schr\"odinger's cat is one of the most striking paradoxes of quantum mechanics that reveals the counterintuitive aspects of the microscopic world. Here, I discuss the paradox in the framework of quantum information.
Ionicioiu, Radu
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Fast and Lightweight Object Detection Network: Detection and Recognition on Resource Constrained Devices

IEEE Access, 2018
The intrinsic ability of humans to rapidly detect, differentiate, and classify objects allows us to make quick decisions in regards to what we see. Several appliances can make use of fast and lightweight automated object detection for images or videos ...
Bernardo Augusto Godinho de Oliveira, Flavia Magalhaes Freitas Ferreira, Carlos Augusto Paiva da Silva Martins   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

The Effects of a Microbial Enzyme Mixture on Macronutrient Hydrolysis in a Static Simulation of Oro-Gastric Digestion That Models Human Digestive Senescence

Foods
Observational studies have shown that human digestive function declines naturally with age. Oral enzyme supplementation is a candidate strategy to enhance macronutrient digestion in older adults.
Sean M. Garvey, Erin N. Madden, Yunyao Qu, Caroline H. Best, Kelly M. Tinker   +4 more
doaj   +1 more source