Results 61 to 70 of about 2,312,470 (291)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Design and ATEX-Aware Kinematic Analysis of a Multi-Body Robot for Gas Pipeline Inspection
IEEE AccessThis paper presents the design and theoretical validation of a multi-body in-pipe inspection robot intended for operation in natural gas pipelines under the ATEX Directive 2014/34/EU.
Franco Rivadeneira +2 more
doaj +1 more source
Wigner functions, squeezing properties and slow decoherence of atomic Schrodinger cats
, 1999 We consider a class of states in an ensemble of two-level atoms: a superposition of two distinct atomic coherent states, which can be regarded as atomic analogues of the states usually called Schrodinger cat states in quantum optics.
A. Czirják +58 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Medicina, 2018 Introducción y objetivo: La respuesta inmune en el embarazo varía de acuerdo a la enfermedad reumática presente. Describir los embarazos de mujeres con enfermedades reumáticas en una Clínica de Artritis Temprana. Métodos: Estudio descriptivo.
María A. Moreno-Salamanca +1 more
doaj
Domestic cat management in the UK: learnings from a global perspective
Frontiers in Veterinary ScienceThe overpopulation of domestic cats has the potential to result in negative outcomes for cats, people and the surrounding environment. A whole-population approach to management requires a system of services considering owned, shelter and free-living ...
Jenni L. McDonald +5 more
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Crime and law enforcement: a quick guide to key internet links [PDF]
This Quick Guide provides key internet links to websites with information on crime and law enforcement arrangements and ...
Cat Barker
core
Feasibility, Acceptability, and Preliminary Outcomes of a Culturally Adapted Evidence-Based Treatment for Latino Youth With ADHD [PDF]
, 2019 Objective: To advance our knowledge about the most effective way to treat Latino youth with ADHD, the current feasibility and pilot study compared a culturally adapted evidence-based treatment (CAT) for ADHD to standard evidence-based treatment (EBT ...
Castro, Al +3 more
core +1 more source