Results 51 to 60 of about 2,312,470 (291)

Wnt/beta-catenin signaling controls development of the blood–brain barrier [PDF]

open access: yes, 2009
The blood–brain barrier (BBB) is confined to the endothelium of brain capillaries and is indispensable for fluid homeostasis and neuronal function. In this study, we show that endothelial Wnt/beta-catenin (beta-cat) signaling regulates induction and ...
Babbage, Jane   +14 more
core  

Completions, branched covers, Artin groups and singularity theory

open access: yes, 2011
We study the curvature of metric spaces and branched covers of Riemannian manifolds, with applications in topology and algebraic geometry. Here curvature bounds are expressed in terms of the CAT(k) inequality. We prove a general CAT(k) extension theorem,
Allcock, Daniel
core   +1 more source

Cat CAT-scan: Postmortem imaging and autopsy of two cats [PDF]

open access: yesJournal of Forensic Radiology and Imaging, 2015
A man killed his wife and their shared household cats before killing himself. The combination of the killing (suicide or homicide) of a family member and the pet is seen on occasions in forensic pathology. The purpose of this case report is to provide a comparison of the killing methods of animals, ill pets and of household animals, also in extended ...
Martinez, Rosa Maria   +3 more
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Supervised Machine Learning Techniques for the Prediction of the State of Charge of Batteries in Photovoltaic Systems in the Mining Sector

open access: yesIEEE Access, 2022
One of the critical aspects in the mining sector is energy, being of great importance for the operation since if it were to stop, one of the consequences would be the loss of large amounts of money.
Alexa Apaza-Pinto   +3 more
doaj   +1 more source

PERBAIKAN BODI DAN PENGECATAN ULANG MOBIL TOYOTA HIACE TAHUN 1981 AB 9010 DN SEBELAH KIRI [PDF]

open access: yes, 2011
Tujuan dari proyek akhir yang berjudul perbaikan dan pengecatan bodi mobil Toyota Hiace Tahun 1981 sebelah kiri adalah untuk melakukan proses rekondisi bodi dan cat mobil Toyota Hiace sebelah kiri dan mengetahui hasil setelah dilakukan perbaikan dan ...
Dyan, Wahyudi
core  

‘Wound cat’

open access: yesJournal of Feline Medicine and Surgery, 2006
‘Wound man’ refers to a stylised diagram used in early medical textbooks to illustrate the various injuries that the human body can sustain in battle. We have adapted this concept to create ‘Wound cat’, as a way to emphasise the type and location of injuries cats may inflict on one another during combat.
Richard, Malik   +3 more
openaire   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

A High-Efficiency RF Harvester with Maximum Power Point Tracking

open access: yesProceedings, 2018
This paper presents the implementation of a high-efficiency radiofrequency (RF) harvester, which consists of a rectenna and a maximum power point tracker (MPPT).
Manel Gasulla   +5 more
doaj   +1 more source

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