Animal‐Free Setup of a 3D Mature Adipocyte‐Macrophage Co‐Culture to Induce Inflammation In Vitro
A completely animal‐free 3D co‐culture is developed using human fat cells and immune cells. Animal‐based materials are replaced with gellan gum hydrogel and a serum‐free medium. Immune cells are effectively activated, producing specific inflammatory signals.
Sophia Nowakowski+3 more
wiley +1 more source
A Discrete Choice Experiment to Assess Cat Owners' Preferences for Topical Antiparasitics and the Comparative Ease of Use of a Combined Selamectin and Sarolaner Formulation: An International Survey. [PDF]
Tsokana CN+9 more
europepmc +1 more source
Peptide Display Directed Assembly of Biopolymer Core–Silica Shell Particles
Bacterial cells are engineered to produce biopolyester particles displaying peptides mediating growth of silica. Peptide‐coated biopolyester particles are treated with silica precursors and silica shell formation is studied. Transmission electron microscopy shows silica‐coated BPs which are formed after the silicification treatment. Characterization of
Deeptee Chandrashekhar Pande+2 more
wiley +1 more source
Comparative Analysis of Oxidative Stress Biomarkers in 50 Primary Open-Angle Glaucoma Patients. [PDF]
Seven E, Tekin S.
europepmc +1 more source
Cat-Scratch Disease Presenting as Multifocal Osteomyelitis With Thoracic Abscess
Sangita P. Modi+2 more
openalex +1 more source
Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery
This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis+6 more
wiley +1 more source
Pilaralisib inhibits the replication of enteroviruses by targeting the PI3K/AKT signaling pathway. [PDF]
Zhou J+10 more
europepmc +1 more source
Cat-scratch Disease Lymphadenitis
Caponetti, Gabriel, MD+1 more
openaire +3 more sources
Rolling Ultrasharp Microneedle Spheres Enable Topical Delivery of Biologics Through the Skin
Rolling ultraminiaturized microneedle spheres (RUMS), created via two‐photon polymerization, unlock effective and painless topical delivery of messenger RNA (mRNA) and drugs through the skin. By gently forming thousands of microscopic pores, RUMS boost skin permeability by up to 100‐fold.
Theocharis Nikiforos Iordanidis+6 more
wiley +1 more source