Results 81 to 90 of about 303,179 (311)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

A prospective study of cat-scratch disease in Lima-Peru

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2002
Cat-Scratch Disease (CSD) is a benign lymphadenitis that may progress to severe or recurrent forms, and it is occasionally associated with morbidity.
HUARCAYA Erick   +8 more
doaj  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Expression of Antioxidant Enzymes in Patients with Uterine Polyp, Myoma, Hyperplasia, and Adenocarcinoma

open access: yesAntioxidants, 2019
We previously found that compared to patients with benign uterine diseases (polyps, myomas), patients with premalignant (hyperplasia simplex and complex) and malignant (adenocarcinoma) lesions had enhanced lipid peroxidation and altered uterine ...
Ana Todorović   +6 more
doaj   +1 more source

Systemic Cat Scratch Disease

open access: yesJournal of the Formosan Medical Association, 2006
Systemic cat scratch disease (CSD) is often associated with prolonged fever and microabscesses in the liver and/or spleen. We report a case of systemic CSD with hepatic, splenic and renal involvement in an aboriginal child in Taiwan. A previously healthy 9-year-old girl had an intermittent fever for about 17 days, and complained of abdominal pain ...
Hui-Min Liao   +4 more
openaire   +3 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Discovery and characterization of the feline miRNAome

open access: yesScientific Reports, 2017
The domestic cat is an important human companion animal that can also serve as a relevant model for ~250 genetic diseases, many metabolic and degenerative conditions, and forms of cancer that are analogous to human disorders.
Alessandro Laganà   +8 more
doaj   +1 more source

Detection of Anaplasma phagocytophilum in a cat

open access: yesVeterinární Medicína, 2013
The aim of this study was to diagnose the etiological factor of disease in a 2.5 year old male cat with symptoms of loss of appetite, apathy and the presence of pale yellow mucous membranes. Haematological and biochemical analysis of the blood taken from
M. Gorna   +4 more
doaj   +1 more source

Cost-Benefit Model System of Chronic Diseases in Australia to Assess and Rank Prevention and Treatment Options [PDF]

open access: yes
Chronic diseases - eg heart disease, cancer, diabetes, mental disorders - affect around 80% of older Australians, are the main causes of disability and premature death, and account for 70% of total health expenditures.
Stephen Colagiuri, Agnes E. Walker
core  

Brain inflammation and the neuronal fate: from neurogenesis to neurodegeneration

open access: yes, 2009
Inflammation is a self-defensive reaction that may develop into a chronic state and become a causative factor in the pathogenesis of a broad range of disabling diseases.
Luisa Minghetti   +2 more
core   +1 more source

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